Robinson DA - Search Results

1

The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.

Roszak AW, Robinson DA, Krell T, Hunter IS, Fredrickson M, Abell C, Coggins JR, Lapthorn AJ. Roszak AW, et al. Among authors: robinson da. Structure. 2002 Apr;10(4):493-503. doi: 10.1016/s0969-2126(02)00747-5. Structure. 2002. PMID: 11937054 Free article.

2

Type II dehydroquinase: molecular replacement with many copies.

Stewart KA, Robinson DA, Lapthorn AJ. Stewart KA, et al. Among authors: robinson da. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):108-18. doi: 10.1107/S0907444907054923. Epub 2007 Dec 5. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18094474 Free PMC article.

3

Specificity of substrate recognition by type II dehydroquinases as revealed by binding of polyanions.

Evans LD, Roszak AW, Noble LJ, Robinson DA, Chalk PA, Matthews JL, Coggins JR, Price NC, Lapthorn AJ. Evans LD, et al. Among authors: robinson da. FEBS Lett. 2002 Oct 23;530(1-3):24-30. doi: 10.1016/s0014-5793(02)03346-x. FEBS Lett. 2002. PMID: 12387860 Free article.

4

Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design.

Robinson DA, Stewart KA, Price NC, Chalk PA, Coggins JR, Lapthorn AJ. Robinson DA, et al. J Med Chem. 2006 Feb 23;49(4):1282-90. doi: 10.1021/jm0505361. J Med Chem. 2006. PMID: 16480265

5

Experiences with the shikimate-pathway enzymes as targets for rational drug design.

Coggins JR, Abell C, Evans LB, Frederickson M, Robinson DA, Roszak AW, Lapthorn AP. Coggins JR, et al. Among authors: robinson da. Biochem Soc Trans. 2003 Jun;31(Pt 3):548-52. doi: 10.1042/bst0310548. Biochem Soc Trans. 2003. PMID: 12773154 Review.

6

Novel ligands for a purine riboswitch discovered by RNA-ligand docking.

Daldrop P, Reyes FE, Robinson DA, Hammond CM, Lilley DM, Batey RT, Brenk R. Daldrop P, et al. Among authors: robinson da. Chem Biol. 2011 Mar 25;18(3):324-35. doi: 10.1016/j.chembiol.2010.12.020. Chem Biol. 2011. PMID: 21439477 Free PMC article.

7

Identification and structure solution of fragment hits against kinetoplastid N-myristoyltransferase.

Robinson DA, Wyatt PG. Robinson DA, et al. Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):586-93. doi: 10.1107/S2053230X15003040. Epub 2015 Apr 21. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25945713 Free PMC article.

8

N-myristoyltransferase is a cell wall target in Aspergillus fumigatus.

Fang W, Robinson DA, Raimi OG, Blair DE, Harrison JR, Lockhart DE, Torrie LS, Ruda GF, Wyatt PG, Gilbert IH, van Aalten DM. Fang W, et al. Among authors: robinson da. ACS Chem Biol. 2015 Jun 19;10(6):1425-34. doi: 10.1021/cb5008647. Epub 2015 Feb 27. ACS Chem Biol. 2015. PMID: 25706802 Free PMC article.

9

One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.

Mpamhanga CP, Spinks D, Tulloch LB, Shanks EJ, Robinson DA, Collie IT, Fairlamb AH, Wyatt PG, Frearson JA, Hunter WN, Gilbert IH, Brenk R. Mpamhanga CP, et al. Among authors: robinson da. J Med Chem. 2009 Jul 23;52(14):4454-65. doi: 10.1021/jm900414x. J Med Chem. 2009. PMID: 19527033 Free PMC article.

10

Targeting a critical step in fungal hexosamine biosynthesis.

Lockhart DEA, Stanley M, Raimi OG, Robinson DA, Boldovjakova D, Squair DR, Ferenbach AT, Fang W, van Aalten DMF. Lockhart DEA, et al. Among authors: robinson da. J Biol Chem. 2020 Jun 26;295(26):8678-8691. doi: 10.1074/jbc.RA120.012985. Epub 2020 Apr 27. J Biol Chem. 2020. PMID: 32341126 Free PMC article.

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