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Page 1
Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Albesa-Jové D, Romero-García J, Sancho-Vaello E, Contreras FX, Rodrigo-Unzueta A, Comino N, Carreras-González A, Arrasate P, Urresti S, Biarnés X, Planas A, Guerin ME. Albesa-Jové D, et al. Among authors: rodrigo unzueta a. Structure. 2017 Jul 5;25(7):1034-1044.e3. doi: 10.1016/j.str.2017.05.009. Epub 2017 Jun 15. Structure. 2017. PMID: 28625787 Free article.
A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Albesa-Jové D, Mendoza F, Rodrigo-Unzueta A, Gomollón-Bel F, Cifuente JO, Urresti S, Comino N, Gómez H, Romero-García J, Lluch JM, Sancho-Vaello E, Biarnés X, Planas A, Merino P, Masgrau L, Guerin ME. Albesa-Jové D, et al. Among authors: rodrigo unzueta a. Angew Chem Int Ed Engl. 2015 Aug 17;54(34):9898-902. doi: 10.1002/anie.201504617. Epub 2015 Jul 1. Angew Chem Int Ed Engl. 2015. PMID: 26136334
Conformational plasticity of the essential membrane-associated mannosyltransferase PimA from mycobacteria.
Giganti D, Alegre-Cebollada J, Urresti S, Albesa-Jové D, Rodrigo-Unzueta A, Comino N, Kachala M, López-Fernández S, Svergun DI, Fernández JM, Guerin ME. Giganti D, et al. Among authors: rodrigo unzueta a. J Biol Chem. 2013 Oct 11;288(41):29797-808. doi: 10.1074/jbc.M113.462705. Epub 2013 Aug 20. J Biol Chem. 2013. PMID: 23963451 Free PMC article.
Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria.
Sancho-Vaello E, Albesa-Jové D, Rodrigo-Unzueta A, Guerin ME. Sancho-Vaello E, et al. Among authors: rodrigo unzueta a. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Nov;1862(11):1355-1367. doi: 10.1016/j.bbalip.2016.11.002. Epub 2016 Nov 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27826050 Review.
Dissecting the Structural and Chemical Determinants of the "Open-to-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria.
Rodrigo-Unzueta A, Ghirardello M, Urresti S, Delso I, Giganti D, Anso I, Trastoy B, Comino N, Tersa M, D'Angelo C, Cifuente JO, Marina A, Liebau J, Mäler L, Chenal A, Albesa-Jové D, Merino P, Guerin ME. Rodrigo-Unzueta A, et al. Biochemistry. 2020 Aug 18;59(32):2934-2945. doi: 10.1021/acs.biochem.0c00376. Epub 2020 Aug 4. Biochemistry. 2020. PMID: 32786405
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
Albesa-Jové D, Chiarelli LR, Makarov V, Pasca MR, Urresti S, Mori G, Salina E, Vocat A, Comino N, Mohorko E, Ryabova S, Pfieiffer B, Lopes Ribeiro AL, Rodrigo-Unzueta A, Tersa M, Zanoni G, Buroni S, Altmann KH, Hartkoorn RC, Glockshuber R, Cole ST, Riccardi G, Guerin ME. Albesa-Jové D, et al. Among authors: rodrigo unzueta a. ACS Chem Biol. 2014 Jul 18;9(7):1567-75. doi: 10.1021/cb500149m. Epub 2014 Jun 13. ACS Chem Biol. 2014. PMID: 24877756 Free article.