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Boosting mitochondrial health to counteract neurodegeneration.
Burtscher J, Romani M, Bernardo G, Popa T, Ziviani E, Hummel FC, Sorrentino V, Millet GP. Burtscher J, et al. Among authors: romani m. Prog Neurobiol. 2022 Aug;215:102289. doi: 10.1016/j.pneurobio.2022.102289. Epub 2022 May 28. Prog Neurobiol. 2022. PMID: 35636655 Free article.
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, D'Amico D, Moullan N, Potenza F, Schmid AW, Rietsch S, Counts SE, Auwerx J. Sorrentino V, et al. Among authors: romani m. Nature. 2017 Dec 14;552(7684):187-193. doi: 10.1038/nature25143. Epub 2017 Dec 6. Nature. 2017. PMID: 29211722 Free PMC article.
The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.
D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J. D'Amico D, et al. Among authors: romani m. Mol Cell. 2019 Feb 21;73(4):775-787.e10. doi: 10.1016/j.molcel.2018.11.034. Epub 2019 Jan 11. Mol Cell. 2019. PMID: 30642763 Free PMC article.
NAD+ homeostasis in health and disease.
Katsyuba E, Romani M, Hofer D, Auwerx J. Katsyuba E, et al. Among authors: romani m. Nat Metab. 2020 Jan;2(1):9-31. doi: 10.1038/s42255-019-0161-5. Epub 2020 Jan 20. Nat Metab. 2020. PMID: 32694684 Review.
The exercise-induced long noncoding RNA CYTOR promotes fast-twitch myogenesis in aging.
Wohlwend M, Laurila PP, Williams K, Romani M, Lima T, Pattawaran P, Benegiamo G, Salonen M, Schneider BL, Lahti J, Eriksson JG, Barrès R, Wisløff U, Moreira JBN, Auwerx J. Wohlwend M, et al. Among authors: romani m. Sci Transl Med. 2021 Dec 8;13(623):eabc7367. doi: 10.1126/scitranslmed.abc7367. Epub 2021 Dec 8. Sci Transl Med. 2021. PMID: 34878822
Niacin: an old lipid drug in a new NAD+ dress.
Romani M, Hofer DC, Katsyuba E, Auwerx J. Romani M, et al. J Lipid Res. 2019 Apr;60(4):741-746. doi: 10.1194/jlr.S092007. Epub 2019 Feb 19. J Lipid Res. 2019. PMID: 30782960 Free PMC article.
Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging.
Lima TI, Laurila PP, Wohlwend M, Morel JD, Goeminne LJE, Li H, Romani M, Li X, Oh CM, Park D, Rodríguez-López S, Ivanisevic J, Gallart-Ayala H, Crisol B, Delort F, Batonnet-Pichon S, Silveira LR, Sankabattula Pavani Veera Venkata L, Padala AK, Jain S, Auwerx J. Lima TI, et al. Among authors: romani m. Sci Transl Med. 2023 May 17;15(696):eade6509. doi: 10.1126/scitranslmed.ade6509. Epub 2023 May 17. Sci Transl Med. 2023. PMID: 37196064
329 results