Rosen DB - Search Results

1

AKT signaling as a novel factor associated with in vitro resistance of human AML to gemtuzumab ozogamicin.

Rosen DB, Harrington KH, Cordeiro JA, Leung LY, Putta S, Lacayo N, Laszlo GS, Gudgeon CJ, Hogge DE, Hawtin RE, Cesano A, Walter RB. Rosen DB, et al. PLoS One. 2013;8(1):e53518. doi: 10.1371/journal.pone.0053518. Epub 2013 Jan 8. PLoS One. 2013. PMID: 23320091 Free PMC article.

2

Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia.

Rosen DB, Putta S, Covey T, Huang YW, Nolan GP, Cesano A, Minden MD, Fantl WJ. Rosen DB, et al. PLoS One. 2010 Aug 25;5(8):e12405. doi: 10.1371/journal.pone.0012405. PLoS One. 2010. PMID: 20811632 Free PMC article.

3

Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).

Rosen DB, Minden MD, Kornblau SM, Cohen A, Gayko U, Putta S, Woronicz J, Evensen E, Fantl WJ, Cesano A. Rosen DB, et al. PLoS One. 2010 Oct 27;5(10):e13543. doi: 10.1371/journal.pone.0013543. PLoS One. 2010. PMID: 21048955 Free PMC article.

4

Assessing signaling pathways associated with in vitro resistance to cytotoxic agents in AML.

Rosen DB, Cordeiro JA, Cohen A, Lacayo N, Hogge D, Hawtin RE, Cesano A. Rosen DB, et al. Leuk Res. 2012 Jul;36(7):900-4. doi: 10.1016/j.leukres.2012.02.022. Epub 2012 Apr 21. Leuk Res. 2012. PMID: 22521550

5

Functional pathway analysis using SCNP of FLT3 receptor pathway deregulation in AML provides prognostic information independent from mutational status.

Cesano A, Putta S, Rosen DB, Cohen AC, Gayko U, Mathi K, Woronicz J, Hawtin RE, Cripe L, Sun Z, Tallman MS, Paietta E. Cesano A, et al. Among authors: rosen db. PLoS One. 2013;8(2):e56714. doi: 10.1371/journal.pone.0056714. Epub 2013 Feb 19. PLoS One. 2013. PMID: 23431389 Free PMC article.

6

Functional pathway analysis in acute myeloid leukemia using single cell network profiling assay: effect of specimen source (bone marrow or peripheral blood) on assay readouts.

Cesano A, Rosen DB, O'Meara P, Putta S, Gayko U, Spellmeyer DC, Cripe LD, Sun Z, Uno H, Litzow MR, Tallman MS, Paietta E. Cesano A, et al. Among authors: rosen db. Cytometry B Clin Cytom. 2012 May;82(3):158-72. doi: 10.1002/cyto.b.21007. Epub 2012 Feb 14. Cytometry B Clin Cytom. 2012. PMID: 22334473 Free PMC article.

7

Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP).

Rosen DB, Leung LY, Louie B, Cordeiro JA, Conroy A, Shapira I, Fields SZ, Cesano A, Hawtin RE. Rosen DB, et al. J Transl Med. 2014 Jun 25;12:184. doi: 10.1186/1479-5876-12-184. J Transl Med. 2014. PMID: 24965603 Free PMC article.

8

Dynamic single-cell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy.

Kornblau SM, Minden MD, Rosen DB, Putta S, Cohen A, Covey T, Spellmeyer DC, Fantl WJ, Gayko U, Cesano A. Kornblau SM, et al. Among authors: rosen db. Clin Cancer Res. 2010 Jul 15;16(14):3721-33. doi: 10.1158/1078-0432.CCR-10-0093. Epub 2010 Jun 4. Clin Cancer Res. 2010. PMID: 20525753 Free PMC article.

9

Development and validation of a single-cell network profiling assay-based classifier to predict response to induction therapy in paediatric patients with de novo acute myeloid leukaemia: a report from the Children's Oncology Group.

Lacayo NJ, Alonzo TA, Gayko U, Rosen DB, Westfall M, Purvis N, Putta S, Louie B, Hackett J, Cohen AC, Cesano A, Gerbing R, Ravindranath Y, Dahl GV, Gamis A, Meshinchi S. Lacayo NJ, et al. Among authors: rosen db. Br J Haematol. 2013 Jul;162(2):250-62. doi: 10.1111/bjh.12370. Epub 2013 May 20. Br J Haematol. 2013. PMID: 23682827 Free PMC article. Clinical Trial.

10

Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development of synthetic lethality.

Leung M, Rosen D, Fields S, Cesano A, Budman DR. Leung M, et al. Mol Med. 2011;17(7-8):854-62. doi: 10.2119/molmed.2010.00240. Epub 2011 Mar 11. Mol Med. 2011. PMID: 21424107 Free PMC article. Review.

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