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SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.
Miorin L, Kehrer T, Sanchez-Aparicio MT, Zhang K, Cohen P, Patel RS, Cupic A, Makio T, Mei M, Moreno E, Danziger O, White KM, Rathnasinghe R, Uccellini M, Gao S, Aydillo T, Mena I, Yin X, Martin-Sancho L, Krogan NJ, Chanda SK, Schotsaert M, Wozniak RW, Ren Y, Rosenberg BR, Fontoura BMA, García-Sastre A. Miorin L, et al. Among authors: rosenberg br. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28344-28354. doi: 10.1073/pnas.2016650117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097660 Free PMC article.
The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response.
Seifert LL, Si C, Saha D, Sadic M, de Vries M, Ballentine S, Briley A, Wang G, Valero-Jimenez AM, Mohamed A, Schaefer U, Moulton HM, García-Sastre A, Tripathi S, Rosenberg BR, Dittmann M. Seifert LL, et al. Among authors: rosenberg br. PLoS Pathog. 2019 Nov 4;15(11):e1007634. doi: 10.1371/journal.ppat.1007634. eCollection 2019 Nov. PLoS Pathog. 2019. PMID: 31682641 Free PMC article.
Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection.
Ho JSY, Angel M, Ma Y, Sloan E, Wang G, Martinez-Romero C, Alenquer M, Roudko V, Chung L, Zheng S, Chang M, Fstkchyan Y, Clohisey S, Dinan AM, Gibbs J, Gifford R, Shen R, Gu Q, Irigoyen N, Campisi L, Huang C, Zhao N, Jones JD, van Knippenberg I, Zhu Z, Moshkina N, Meyer L, Noel J, Peralta Z, Rezelj V, Kaake R, Rosenberg B, Wang B, Wei J, Paessler S, Wise HM, Johnson J, Vannini A, Amorim MJ, Baillie JK, Miraldi ER, Benner C, Brierley I, Digard P, Łuksza M, Firth AE, Krogan N, Greenbaum BD, MacLeod MK, van Bakel H, Garcìa-Sastre A, Yewdell JW, Hutchinson E, Marazzi I. Ho JSY, et al. Cell. 2020 Jun 25;181(7):1502-1517.e23. doi: 10.1016/j.cell.2020.05.035. Epub 2020 Jun 18. Cell. 2020. PMID: 32559462 Free PMC article.
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells.
Daniloski Z, Jordan TX, Wessels HH, Hoagland DA, Kasela S, Legut M, Maniatis S, Mimitou EP, Lu L, Geller E, Danziger O, Rosenberg BR, Phatnani H, Smibert P, Lappalainen T, tenOever BR, Sanjana NE. Daniloski Z, et al. Among authors: rosenberg br. Cell. 2021 Jan 7;184(1):92-105.e16. doi: 10.1016/j.cell.2020.10.030. Epub 2020 Oct 24. Cell. 2021. PMID: 33147445 Free PMC article.
The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication.
Nilsson-Payant BE, Uhl S, Grimont A, Doane AS, Cohen P, Patel RS, Higgins CA, Acklin JA, Bram Y, Chandar V, Blanco-Melo D, Panis M, Lim JK, Elemento O, Schwartz RE, Rosenberg BR, Chandwani R, tenOever BR. Nilsson-Payant BE, et al. Among authors: rosenberg br. J Virol. 2021 Nov 9;95(23):e0125721. doi: 10.1128/JVI.01257-21. Epub 2021 Sep 15. J Virol. 2021. PMID: 34523966 Free PMC article.
Limited extent and consequences of pancreatic SARS-CoV-2 infection.
van der Heide V, Jangra S, Cohen P, Rathnasinghe R, Aslam S, Aydillo T, Geanon D, Handler D, Kelley G, Lee B, Rahman A, Dawson T, Qi J, D'Souza D, Kim-Schulze S, Panzer JK, Caicedo A, Kusmartseva I, Posgai AL, Atkinson MA, Albrecht RA, García-Sastre A, Rosenberg BR, Schotsaert M, Homann D. van der Heide V, et al. Among authors: rosenberg br. Cell Rep. 2022 Mar 15;38(11):110508. doi: 10.1016/j.celrep.2022.110508. Epub 2022 Feb 21. Cell Rep. 2022. PMID: 35247306 Free PMC article.
SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication.
Higgins CA, Nilsson-Payant BE, Bonaventure B, Kurland AP, Ye C, Yaron TM, Johnson JL, Adhikary P, Golynker I, Panis M, Danziger O, Rosenberg BR, Cantley LC, Martínez-Sobrido L, tenOever B, Johnson JR. Higgins CA, et al. Among authors: rosenberg br. mBio. 2023 Aug 31;14(4):e0100723. doi: 10.1128/mbio.01007-23. Epub 2023 Jun 22. mBio. 2023. PMID: 37345956 Free PMC article.
42 results