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Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.
Sondhi D, Kaminsky SM, Hackett NR, Pagovich OE, Rosenberg JB, De BP, Chen A, Van de Graaf B, Mezey JG, Mammen GW, Mancenido D, Xu F, Kosofsky B, Yohay K, Worgall S, Kaner RJ, Souwedaine M, Greenwald BM, Kaplitt M, Dyke JP, Ballon DJ, Heier LA, Kiss S, Crystal RG. Sondhi D, et al. Among authors: rosenberg jb. Sci Transl Med. 2020 Dec 2;12(572):eabb5413. doi: 10.1126/scitranslmed.abb5413. Sci Transl Med. 2020. PMID: 33268510 Free PMC article. Clinical Trial.
Anti-cocaine vaccine based on coupling a cocaine analog to a disrupted adenovirus.
Koob G, Hicks MJ, Wee S, Rosenberg JB, De BP, Kaminsky SM, Moreno A, Janda KD, Crystal RG. Koob G, et al. Among authors: rosenberg jb. CNS Neurol Disord Drug Targets. 2011 Dec;10(8):899-904. doi: 10.2174/187152711799219334. CNS Neurol Disord Drug Targets. 2011. PMID: 22229312 Free PMC article. Review.
Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.
Maoz A, Hicks MJ, Vallabhjosula S, Synan M, Kothari PJ, Dyke JP, Ballon DJ, Kaminsky SM, De BP, Rosenberg JB, Martinez D, Koob GF, Janda KD, Crystal RG. Maoz A, et al. Among authors: rosenberg jb. Neuropsychopharmacology. 2013 Oct;38(11):2170-8. doi: 10.1038/npp.2013.114. Epub 2013 May 10. Neuropsychopharmacology. 2013. PMID: 23660705 Free PMC article.
99 results