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17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex.
Harrison DE, Strong R, Reifsnyder P, Kumar N, Fernandez E, Flurkey K, Javors MA, Lopez-Cruzan M, Macchiarini F, Nelson JF, Markewych A, Bitto A, Sindler AL, Cortopassi G, Kavanagh K, Leng L, Bucala R, Rosenthal N, Salmon A, Stearns TM, Bogue M, Miller RA. Harrison DE, et al. Among authors: rosenthal n. Aging Cell. 2021 May;20(5):e13328. doi: 10.1111/acel.13328. Epub 2021 Mar 31. Aging Cell. 2021. PMID: 33788371 Free PMC article.
Canagliflozin extends life span in genetically heterogeneous male but not female mice.
Miller RA, Harrison DE, Allison DB, Bogue M, Debarba L, Diaz V, Fernandez E, Galecki A, Garvey WT, Jayarathne H, Kumar N, Javors MA, Ladiges WC, Macchiarini F, Nelson J, Reifsnyder P, Rosenthal NA, Sadagurski M, Salmon AB, Smith DL Jr, Snyder JM, Lombard DB, Strong R. Miller RA, et al. Among authors: rosenthal na. JCI Insight. 2020 Nov 5;5(21):e140019. doi: 10.1172/jci.insight.140019. JCI Insight. 2020. PMID: 32990681 Free PMC article.
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice.
Strong R, Miller RA, Cheng CJ, Nelson JF, Gelfond J, Allani SK, Diaz V, Dorigatti AO, Dorigatti J, Fernandez E, Galecki A, Ginsburg B, Hamilton KL, Javors MA, Kornfeld K, Kaeberlein M, Kumar S, Lombard DB, Lopez-Cruzan M, Miller BF, Rabinovitch P, Reifsnyder P, Rosenthal NA, Bogue MA, Salmon AB, Suh Y, Verdin E, Weissbach H, Newman J, Maccchiarini F, Harrison DE. Strong R, et al. Aging Cell. 2022 Dec;21(12):e13724. doi: 10.1111/acel.13724. Epub 2022 Sep 30. Aging Cell. 2022. PMID: 36179270 Free PMC article.
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice.
Snyder JM, Casey KM, Galecki A, Harrison DE, Jayarathne H, Kumar N, Macchiarini F, Rosenthal N, Sadagurski M, Salmon AB, Strong R, Miller RA, Ladiges W. Snyder JM, et al. Among authors: rosenthal n. Geroscience. 2023 Feb;45(1):385-397. doi: 10.1007/s11357-022-00641-0. Epub 2022 Aug 16. Geroscience. 2023. PMID: 35974129 Free PMC article.
Fibroblasts: Origins, definitions, and functions in health and disease.
Plikus MV, Wang X, Sinha S, Forte E, Thompson SM, Herzog EL, Driskell RR, Rosenthal N, Biernaskie J, Horsley V. Plikus MV, et al. Among authors: rosenthal n. Cell. 2021 Jul 22;184(15):3852-3872. doi: 10.1016/j.cell.2021.06.024. Cell. 2021. PMID: 34297930 Free PMC article. Review.
Homeobox genes and muscle patterning.
Olson EN, Rosenthal N. Olson EN, et al. Among authors: rosenthal n. Cell. 1994 Oct 7;79(1):9-12. doi: 10.1016/0092-8674(94)90395-6. Cell. 1994. PMID: 7923381 Review. No abstract available.
Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.
Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW. Furtado MB, et al. Among authors: rosenthal na. JCI Insight. 2017 Mar 23;2(6):e88271. doi: 10.1172/jci.insight.88271. JCI Insight. 2017. PMID: 28352650 Free PMC article.
692 results