Rossjohn J - Search Results

1

Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses.

Loh L, Gherardin NA, Sant S, Grzelak L, Crawford JC, Bird NL, Koay HF, van de Sandt CE, Moreira ML, Lappas M, Allen EK, Crowe J, Loudovaris T, Flanagan KL, Quinn KM, Rossjohn J, Thomas PG, Eckle SBG, McCluskey J, Godfrey DI, Kedzierska K. Loh L, et al. Among authors: rossjohn j. J Immunol. 2020 Mar 1;204(5):1119-1133. doi: 10.4049/jimmunol.1900774. Epub 2020 Jan 27. J Immunol. 2020. PMID: 31988181 Clinical Trial.

2

Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex.

Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Macdonald W, et al. Among authors: rossjohn j. FEBS Lett. 2002 Sep 11;527(1-3):27-32. doi: 10.1016/s0014-5793(02)03149-6. FEBS Lett. 2002. PMID: 12220628 Free article.

3

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, Fontes MR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: rossjohn j. J Immunol. 2002 Nov 1;169(9):5153-60. doi: 10.4049/jimmunol.169.9.5153. J Immunol. 2002. PMID: 12391232

4

The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.

Kjer-Nielsen L, Clements CS, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: rossjohn j. Structure. 2002 Nov;10(11):1521-32. doi: 10.1016/s0969-2126(02)00878-x. Structure. 2002. PMID: 12429093 Free article.

5

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.

Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Clements CS, et al. Among authors: rossjohn j. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2131-4. doi: 10.1107/s0907444902015482. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454477

6

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity.

Kjer-Nielsen L, Clements CS, Purcell AW, Brooks AG, Whisstock JC, Burrows SR, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: rossjohn j. Immunity. 2003 Jan;18(1):53-64. doi: 10.1016/s1074-7613(02)00513-7. Immunity. 2003. PMID: 12530975 Free article.

7

Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue.

Webb AI, Dunstone MA, Chen W, Aguilar MI, Chen Q, Jackson H, Chang L, Kjer-Nielsen L, Beddoe T, McCluskey J, Rossjohn J, Purcell AW. Webb AI, et al. Among authors: rossjohn j. J Biol Chem. 2004 May 28;279(22):23438-46. doi: 10.1074/jbc.M314066200. Epub 2004 Mar 5. J Biol Chem. 2004. PMID: 15004033 Free article.

8

Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

Kjer-Nielsen L, Dunstone MA, Kostenko L, Ely LK, Beddoe T, Mifsud NA, Purcell AW, Brooks AG, McCluskey J, Rossjohn J. Kjer-Nielsen L, et al. Among authors: rossjohn j. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7675-80. doi: 10.1073/pnas.0402295101. Epub 2004 May 10. Proc Natl Acad Sci U S A. 2004. PMID: 15136729 Free PMC article.

9

The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.

Webb AI, Borg NA, Dunstone MA, Kjer-Nielsen L, Beddoe T, McCluskey J, Carbone FR, Bottomley SP, Aguilar MI, Purcell AW, Rossjohn J. Webb AI, et al. Among authors: rossjohn j. J Immunol. 2004 Jul 1;173(1):402-9. doi: 10.4049/jimmunol.173.1.402. J Immunol. 2004. PMID: 15210799

10

The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody.

Dunstone MA, Kjer-Nielsen L, Kostenko L, Purcell AW, Brooks AG, Rossjohn J, McCluskey J. Dunstone MA, et al. Among authors: rossjohn j. Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1425-8. doi: 10.1107/S0907444904012041. Epub 2004 Jul 21. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15272166

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