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Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy.
Cell Rep. 2021 Mar 16;34(11):108857. doi: 10.1016/j.celrep.2021.108857.
Cell Rep. 2021.
PMID: 33730565
Free article.
FAT10 is phosphorylated by IKKβ to inhibit the antiviral type-I interferon response.
Saxena K, Roverato ND, Reithmann M, Mah MM, Schregle R, Schmidtke G, Silbern I, Urlaub H, Aichem A.
Saxena K, et al. Among authors: roverato nd.
Life Sci Alliance. 2023 Nov 8;7(1):e202101282. doi: 10.26508/lsa.202101282. Print 2024 Jan.
Life Sci Alliance. 2023.
PMID: 37940187
Free PMC article.
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