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2013 1
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Page 1
Frentizole derivatives with mTOR inhibiting and senomorphic properties.
Chrienova Z, Rysanek D, Novak J, Vasicova P, Oleksak P, Andrys R, Skarka A, Dumanovic J, Milovanovic Z, Jacevic V, Chvojkova M, Holubova K, Vales K, Skoupilova V, Valko M, Jomova K, Alomar SY, Botelho FD, Franca TCC, Kuca K, Hodny Z, Nepovimova E. Chrienova Z, et al. Among authors: andrys r. Biomed Pharmacother. 2023 Nov;167:115600. doi: 10.1016/j.biopha.2023.115600. Epub 2023 Sep 30. Biomed Pharmacother. 2023. PMID: 37783152 Free article.
Nanomolar Benzothiazole-Based Inhibitors of 17β-HSD10 with Cellular Bioactivity.
Hanzlova M, Miskerikova MS, Rotterova A, Chalupova K, Jurkova K, Hamsikova M, Andrys R, Haleckova A, Svobodova J, Schmidt M, Benek O, Musilek K. Hanzlova M, et al. Among authors: andrys r. ACS Med Chem Lett. 2023 Nov 10;14(12):1724-1732. doi: 10.1021/acsmedchemlett.3c00355. eCollection 2023 Dec 14. ACS Med Chem Lett. 2023. PMID: 38116418
Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.
Benek O, Vaskova M, Miskerikova M, Schmidt M, Andrys R, Rotterova A, Skarka A, Hatlapatkova J, Karasova JZ, Medvecky M, Hroch L, Vinklarova L, Fisar Z, Hroudova J, Handl J, Capek J, Rousar T, Kobrlova T, Dolezal R, Soukup O, Aitken L, Gunn-Moore F, Musilek K. Benek O, et al. Among authors: andrys r. Eur J Med Chem. 2023 Oct 5;258:115593. doi: 10.1016/j.ejmech.2023.115593. Epub 2023 Jun 24. Eur J Med Chem. 2023. PMID: 37390508
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities.
Chrienova Z, Nepovimova E, Andrys R, Dolezal R, Janockova J, Muckova L, Fabova L, Soukup O, Oleksak P, Valis M, Korabecny J, Marco-Contelles J, Kuca K. Chrienova Z, et al. Among authors: andrys r. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2605-2620. doi: 10.1080/14756366.2022.2122054. J Enzyme Inhib Med Chem. 2022. PMID: 36131624 Free PMC article.
Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics.
Chrienova Z, Rysanek D, Oleksak P, Stary D, Bajda M, Reinis M, Mikyskova R, Novotny O, Andrys R, Skarka A, Vasicova P, Novak J, Valis M, Kuca K, Hodny Z, Nepovimova E. Chrienova Z, et al. Among authors: andrys r. Front Aging Neurosci. 2022 Dec 6;14:1048260. doi: 10.3389/fnagi.2022.1048260. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36561137 Free PMC article.
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
Svobodova B, Pulkrabkova L, Panek D, Misiachna A, Kolcheva M, Andrys R, Handl J, Capek J, Nyvltova P, Rousar T, Prchal L, Hepnarova V, Hrabinova M, Muckova L, Tosnerova D, Karabanovich G, Finger V, Soukup O, Horak M, Korabecny J. Svobodova B, et al. Among authors: andrys r. Int J Mol Sci. 2023 May 23;24(11):9124. doi: 10.3390/ijms24119124. Int J Mol Sci. 2023. PMID: 37298087 Free PMC article.
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
Bautista-Aguilera ÓM, Ismaili L, Chioua M, Andrys R, Schmidt M, Bzonek P, Martínez-Grau MÁ, Beadle CD, Vetman T, López-Muñoz F, Iriepa I, Refouvelet B, Musilek K, Marco-Contelles J. Bautista-Aguilera ÓM, et al. Among authors: andrys r. Int J Mol Sci. 2020 May 30;21(11):3913. doi: 10.3390/ijms21113913. Int J Mol Sci. 2020. PMID: 32486316 Free PMC article.
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
Mezeiova E, Janockova J, Andrys R, Soukup O, Kobrlova T, Muckova L, Pejchal J, Simunkova M, Handl J, Micankova P, Capek J, Rousar T, Hrabinova M, Nepovimova E, Marco-Contelles JL, Valko M, Korabecny J. Mezeiova E, et al. Among authors: andrys r. Eur J Med Chem. 2021 Feb 5;211:113112. doi: 10.1016/j.ejmech.2020.113112. Epub 2020 Dec 18. Eur J Med Chem. 2021. PMID: 33360800
40 results