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Histone demethylase KDM5D upregulation drives sex differences in colon cancer.
Li J, Lan Z, Liao W, Horner JW, Xu X, Liu J, Yoshihama Y, Jiang S, Shim HS, Slotnik M, LaBella KA, Wu CJ, Dunner K Jr, Hsu WH, Lee R, Khanduri I, Terranova C, Akdemir K, Chakravarti D, Shang X, Spring DJ, Wang YA, DePinho RA. Li J, et al. Among authors: lee r. Nature. 2023 Jul;619(7970):632-639. doi: 10.1038/s41586-023-06254-7. Epub 2023 Jun 21. Nature. 2023. PMID: 37344599 Free PMC article.
Telomere dysfunction instigates inflammation in inflammatory bowel disease.
Chakravarti D, Lee R, Multani AS, Santoni A, Keith Z, Hsu WH, Chang K, Reyes L, Rashid A, Wu CJ, Li J, Zhang J, Shim HS, Chandra K, Deng P, Spring DJ, Nielsen OH, Riis LB, Mayigegowda KK, Blutt SE, Zhang J, Younes M, DuPont A, Thirumurthi S, Vilar E, Estes MK, Colla S, Shroyer NF, DePinho RA. Chakravarti D, et al. Among authors: lee r. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2024853118. doi: 10.1073/pnas.2024853118. Proc Natl Acad Sci U S A. 2021. PMID: 34253611 Free PMC article.
An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer.
Lu X, Pan X, Wu CJ, Zhao D, Feng S, Zang Y, Lee R, Khadka S, Amin SB, Jin EJ, Shang X, Deng P, Luo Y, Morgenlander WR, Weinrich J, Lu X, Jiang S, Chang Q, Navone NM, Troncoso P, DePinho RA, Wang YA. Lu X, et al. Among authors: lee r. Cancer Res. 2018 Jul 15;78(14):3823-3833. doi: 10.1158/0008-5472.CAN-17-3564. Epub 2018 May 16. Cancer Res. 2018. PMID: 29769196 Free PMC article.