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Purification, crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor beta-induced protein (TGFBIp).
Runager K, García-Castellanos R, Valnickova Z, Kristensen T, Nielsen NC, Klintworth GK, Gomis-Rüth FX, Enghild JJ. Runager K, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Mar 1;65(Pt 3):299-303. doi: 10.1107/S1744309109005016. Epub 2009 Feb 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19255489 Free PMC article.
Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp.
Runager K, Basaiawmoit RV, Deva T, Andreasen M, Valnickova Z, Sørensen CS, Karring H, Thøgersen IB, Christiansen G, Underhaug J, Kristensen T, Nielsen NC, Klintworth GK, Otzen DE, Enghild JJ. Runager K, et al. J Biol Chem. 2011 Feb 18;286(7):4951-8. doi: 10.1074/jbc.M110.181099. Epub 2010 Dec 6. J Biol Chem. 2011. PMID: 21135107 Free PMC article.
Polymorphic fibrillation of the destabilized fourth fasciclin-1 domain mutant A546T of the Transforming growth factor-β-induced protein (TGFBIp) occurs through multiple pathways with different oligomeric intermediates.
Andreasen M, Nielsen SB, Runager K, Christiansen G, Nielsen NC, Enghild JJ, Otzen DE. Andreasen M, et al. Among authors: runager k. J Biol Chem. 2012 Oct 5;287(41):34730-42. doi: 10.1074/jbc.M112.379552. Epub 2012 Aug 14. J Biol Chem. 2012. PMID: 22893702 Free PMC article.
Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization.
Underhaug J, Koldsø H, Runager K, Nielsen JT, Sørensen CS, Kristensen T, Otzen DE, Karring H, Malmendal A, Schiøtt B, Enghild JJ, Nielsen NC. Underhaug J, et al. Among authors: runager k. Biochim Biophys Acta. 2013 Dec;1834(12):2812-22. doi: 10.1016/j.bbapap.2013.10.008. Epub 2013 Oct 12. Biochim Biophys Acta. 2013. PMID: 24129074 Free PMC article.
Comparison of two phenotypically distinct lattice corneal dystrophies caused by mutations in the transforming growth factor beta induced (TGFBI) gene.
Poulsen ET, Runager K, Risør MW, Dyrlund TF, Scavenius C, Karring H, Praetorius J, Vorum H, Otzen DE, Klintworth GK, Enghild JJ. Poulsen ET, et al. Among authors: runager k. Proteomics Clin Appl. 2014 Apr;8(3-4):168-77. doi: 10.1002/prca.201300058. Epub 2014 Feb 16. Proteomics Clin Appl. 2014. PMID: 24302499 Free PMC article.
24 results