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Circadian rhythm disruption impairs tissue homeostasis and exacerbates chronic inflammation in the intestine.
Pagel R, Bär F, Schröder T, Sünderhauf A, Künstner A, Ibrahim SM, Autenrieth SE, Kalies K, König P, Tsang AH, Bettenworth D, Divanovic S, Lehnert H, Fellermann K, Oster H, Derer S, Sina C. Pagel R, et al. Among authors: sunderhauf a. FASEB J. 2017 Nov;31(11):4707-4719. doi: 10.1096/fj.201700141RR. Epub 2017 Jul 14. FASEB J. 2017. PMID: 28710114 Free PMC article.
Endogenous circadian clocks regulate 24-h rhythms of physiology and behavior. Circadian rhythm disruption (CRD) is suggested as a risk factor for inflammatory bowel disease. However, the underlying molecular mechanisms remain unknown. ...CRD increases intestinal necroptosi …
Endogenous circadian clocks regulate 24-h rhythms of physiology and behavior. Circadian rhythm disruption (CRD) is suggested as a ris …
Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis.
Schröder T, Kucharczyk D, Bär F, Pagel R, Derer S, Jendrek ST, Sünderhauf A, Brethack AK, Hirose M, Möller S, Künstner A, Bischof J, Weyers I, Heeren J, Koczan D, Schmid SM, Divanovic S, Giles DA, Adamski J, Fellermann K, Lehnert H, Köhl J, Ibrahim S, Sina C. Schröder T, et al. Among authors: sunderhauf a. Mol Metab. 2016 Feb 2;5(4):283-295. doi: 10.1016/j.molmet.2016.01.010. eCollection 2016 Apr. Mol Metab. 2016. PMID: 27069868 Free PMC article.
Short-term high-fat diet feeding protects from the development of experimental allergic asthma in mice.
Schröder T, Wiese AV, Ender F, Quell KM, Vollbrandt T, Duhn J, Sünderhauf A, Künstner A, Moreno-Fernandez ME, Derer S, Aherrahrou Z, Lewkowich I, Divanovic S, Sina C, Köhl J, Laumonnier Y. Schröder T, et al. Among authors: sunderhauf a. Clin Exp Allergy. 2019 Sep;49(9):1245-1257. doi: 10.1111/cea.13454. Epub 2019 Aug 13. Clin Exp Allergy. 2019. PMID: 31265181
Loss of Mucosal p32/gC1qR/HABP1 Triggers Energy Deficiency and Impairs Goblet Cell Differentiation in Ulcerative Colitis.
Sünderhauf A, Hicken M, Schlichting H, Skibbe K, Ragab M, Raschdorf A, Hirose M, Schäffler H, Bokemeyer A, Bettenworth D, Savitt AG, Perner S, Ibrahim S, Peerschke EI, Ghebrehiwet B, Derer S, Sina C. Sünderhauf A, et al. Cell Mol Gastroenterol Hepatol. 2021;12(1):229-250. doi: 10.1016/j.jcmgh.2021.01.017. Epub 2021 Jan 27. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33515804 Free PMC article.
Colorectal Cancer Progression Is Potently Reduced by a Glucose-Free, High-Protein Diet: Comparison to Anti-EGFR Therapy.
Skibbe K, Brethack AK, Sünderhauf A, Ragab M, Raschdorf A, Hicken M, Schlichting H, Preira J, Brandt J, Castven D, Föh B, Pagel R, Marquardt JU, Sina C, Derer S. Skibbe K, et al. Among authors: sunderhauf a. Cancers (Basel). 2021 Nov 19;13(22):5817. doi: 10.3390/cancers13225817. Cancers (Basel). 2021. PMID: 34830971 Free PMC article.
Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.
Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S. Giles DA, et al. Among authors: sunderhauf a. Nat Med. 2017 Jul;23(7):829-838. doi: 10.1038/nm.4346. Epub 2017 Jun 12. Nat Med. 2017. PMID: 28604704 Free PMC article.
GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells.
Sünderhauf A, Raschdorf A, Hicken M, Schlichting H, Fetzer F, Brethack AK, Perner S, Kemper C, Ghebrehiwet B, Sina C, Derer S. Sünderhauf A, et al. Front Oncol. 2020 Sep 30;10:575854. doi: 10.3389/fonc.2020.575854. eCollection 2020. Front Oncol. 2020. PMID: 33102234 Free PMC article.
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