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Metabolomic Profiles Differentiate Scleroderma-PAH From Idiopathic PAH and Correspond With Worsened Functional Capacity.
Alotaibi M, Shao J, Pauciulo MW, Nichols WC, Hemnes AR, Malhotra A, Kim NH, Yuan JX, Fernandes T, Kerr KM, Alshawabkeh L, Desai AA, Bujor AM, Lafyatis R, Watrous JD, Long T, Cheng S, Chan SY, Jain M. Alotaibi M, et al. Chest. 2023 Jan;163(1):204-215. doi: 10.1016/j.chest.2022.08.2230. Epub 2022 Sep 7. Chest. 2023. PMID: 36087794 Free PMC article.
A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts.
Tuomisto K, Palmu J, Long T, Watrous JD, Mercader K, Lagerborg KA, Andres A, Salmi M, Jalkanen S, Vasan RS, Inouye M, Havulinna AS, Tuomilehto J, Jousilahti P, Niiranen TJ, Cheng S, Jain M, Salomaa V. Tuomisto K, et al. BMJ Open Diabetes Res Care. 2022 Mar;10(2):e002519. doi: 10.1136/bmjdrc-2021-002519. BMJ Open Diabetes Res Care. 2022. PMID: 35361620 Free PMC article.
Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.
Chu X, Jaeger M, Beumer J, Bakker OB, Aguirre-Gamboa R, Oosting M, Smeekens SP, Moorlag S, Mourits VP, Koeken VACM, de Bree C, Jansen T, Mathews IT, Dao K, Najhawan M, Watrous JD, Joosten I, Sharma S, Koenen HJPM, Withoff S, Jonkers IH, Netea-Maier RT, Xavier RJ, Franke L, Xu CJ, Joosten LAB, Sanna S, Jain M, Kumar V, Clevers H, Wijmenga C, Netea MG, Li Y. Chu X, et al. Genome Biol. 2021 Jul 6;22(1):198. doi: 10.1186/s13059-021-02413-z. Genome Biol. 2021. PMID: 34229738 Free PMC article.
The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.
Golden E, Rashwan R, Woodward EA, Sgro A, Wang E, Sorolla A, Waryah C, Tie WJ, Cuyàs E, Ratajska M, Kardaś I, Kozlowski P, Johnstone EKM, See HB, Duffy C, Parry J, Lagerborg KA, Czapiewski P, Menendez JA, Gorczyński A, Wasag B, Pfleger KDG, Curtis C, Lee BK, Kim J, Cursons J, Pavlos NJ, Biernat W, Jain M, Woo AJ, Redfern A, Blancafort P. Golden E, et al. Nat Commun. 2021 Mar 26;12(1):1920. doi: 10.1038/s41467-021-22101-7. Nat Commun. 2021. PMID: 33772001 Free PMC article.
42 results