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Activation of Dopamine Receptor 2 Prompts Transcriptomic and Metabolic Plasticity in Glioblastoma.
Caragher SP, Shireman JM, Huang M, Miska J, Atashi F, Baisiwala S, Hong Park C, Saathoff MR, Warnke L, Xiao T, Lesniak MS, James CD, Meltzer H, Tryba AK, Ahmed AU. Caragher SP, et al. Among authors: saathoff mr. J Neurosci. 2019 Mar 13;39(11):1982-1993. doi: 10.1523/JNEUROSCI.1589-18.2018. Epub 2019 Jan 16. J Neurosci. 2019. PMID: 30651332 Free PMC article.
LNX1 Modulates Notch1 Signaling to Promote Expansion of the Glioma Stem Cell Population during Temozolomide Therapy in Glioblastoma.
Baisiwala S, Hall RR 3rd, Saathoff MR, M Shireman J, Park C, Budhiraja S, Goel C, Warnke L, Hardiman C, Wang JY, McCortney K, Horbinski CM, Ahmed AU. Baisiwala S, et al. Among authors: saathoff mr. Cancers (Basel). 2020 Nov 25;12(12):3505. doi: 10.3390/cancers12123505. Cancers (Basel). 2020. PMID: 33255632 Free PMC article.
De novo purine biosynthesis is a major driver of chemoresistance in glioblastoma.
Shireman JM, Atashi F, Lee G, Ali ES, Saathoff MR, Park CH, Savchuk S, Baisiwala S, Miska J, Lesniak MS, James CD, Stupp R, Kumthekar P, Horbinski CM, Ben-Sahra I, Ahmed AU. Shireman JM, et al. Among authors: saathoff mr. Brain. 2021 May 7;144(4):1230-1246. doi: 10.1093/brain/awab020. Brain. 2021. PMID: 33855339 Free PMC article.
ARF4-mediated retrograde trafficking as a driver of chemoresistance in GBM.
Budhiraja S, McManus G, Baisiwala S, Perrault EN, Cho S, Saathoff M, Chen L, Park CH, Kazi HA, Dmello C, Lin P, James CD, Sonabend AM, Heiland DH, Ahmed AU. Budhiraja S, et al. Neuro Oncol. 2024 Mar 20:noae059. doi: 10.1093/neuonc/noae059. Online ahead of print. Neuro Oncol. 2024. PMID: 38506351