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Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark.
Dai L, Peng C, Montellier E, Lu Z, Chen Y, Ishii H, Debernardi A, Buchou T, Rousseaux S, Jin F, Sabari BR, Deng Z, Allis CD, Ren B, Khochbin S, Zhao Y. Dai L, et al. Among authors: sabari br. Nat Chem Biol. 2014 May;10(5):365-70. doi: 10.1038/nchembio.1497. Epub 2014 Mar 30. Nat Chem Biol. 2014. PMID: 24681537
SnapShot: histone modifications.
Huang H, Sabari BR, Garcia BA, Allis CD, Zhao Y. Huang H, et al. Among authors: sabari br. Cell. 2014 Oct 9;159(2):458-458.e1. doi: 10.1016/j.cell.2014.09.037. Cell. 2014. PMID: 25303536 Free PMC article. No abstract available.
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Panwalkar P, Tamrazi B, Dang D, Chung C, Sweha S, Natarajan SK, Pun M, Bayliss J, Ogrodzinski MP, Pratt D, Mullan B, Hawes D, Yang F, Lu C, Sabari BR, Achreja A, Heon J, Animasahun O, Cieslik M, Dunham C, Yip S, Hukin J, Phillips JJ, Bornhorst M, Griesinger AM, Donson AM, Foreman NK, Garton HJL, Heth J, Muraszko K, Nazarian J, Koschmann C, Jiang L, Filbin MG, Nagrath D, Kool M, Korshunov A, Pfister SM, Gilbertson RJ, Allis CD, Chinnaiyan AM, Lunt SY, Blüml S, Judkins AR, Venneti S. Panwalkar P, et al. Among authors: sabari br. Sci Transl Med. 2021 Oct 6;13(614):eabc0497. doi: 10.1126/scitranslmed.abc0497. Epub 2021 Oct 6. Sci Transl Med. 2021. PMID: 34613815 Free PMC article.
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates.
Guo YE, Manteiga JC, Henninger JE, Sabari BR, Dall'Agnese A, Hannett NM, Spille JH, Afeyan LK, Zamudio AV, Shrinivas K, Abraham BJ, Boija A, Decker TM, Rimel JK, Fant CB, Lee TI, Cisse II, Sharp PA, Taatjes DJ, Young RA. Guo YE, et al. Among authors: sabari br. Nature. 2019 Aug;572(7770):543-548. doi: 10.1038/s41586-019-1464-0. Epub 2019 Aug 7. Nature. 2019. PMID: 31391587 Free PMC article.
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas.
Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari B, Margol AS, Panwalkar P, Parolia A, Pekmezci M, McEachin RC, Cieslik M, Tamrazi B, Garcia BA, La Rocca G, Santi M, Lewis PW, Hawkins C, Melnick A, David Allis C, Thompson CB, Chinnaiyan AM, Judkins AR, Venneti S. Bayliss J, et al. Sci Transl Med. 2016 Nov 23;8(366):366ra161. doi: 10.1126/scitranslmed.aah6904. Sci Transl Med. 2016. PMID: 27881822 Free PMC article.
24 results