Sachse G - Search Results

1

FTO influences adipogenesis by regulating mitotic clonal expansion.

Merkestein M, Laber S, McMurray F, Andrew D, Sachse G, Sanderson J, Li M, Usher S, Sellayah D, Ashcroft FM, Cox RD. Merkestein M, et al. Among authors: sachse g. Nat Commun. 2015 Apr 17;6:6792. doi: 10.1038/ncomms7792. Nat Commun. 2015. PMID: 25881961 Free PMC article.

2

The value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation.

O'Connell SM, Proks P, Kramer H, Mattis KK, Sachse G, Joyce C, Houghton JA, Ellard S, Hattersley AT, Ashcroft FM, O'Riordan SM. O'Connell SM, et al. Among authors: sachse g. Clin Case Rep. 2015 Oct;3(10):884-7. doi: 10.1002/ccr3.370. Epub 2015 Sep 8. Clin Case Rep. 2015. PMID: 26509030 Free PMC article.

3

Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels.

Proks P, Puljung MC, Vedovato N, Sachse G, Mulvaney R, Ashcroft FM. Proks P, et al. Among authors: sachse g. Philos Trans R Soc Lond B Biol Sci. 2016 Aug 5;371(1700):20150426. doi: 10.1098/rstb.2015.0426. Philos Trans R Soc Lond B Biol Sci. 2016. PMID: 27377720 Free PMC article. Review.

4

FTO demethylase activity is essential for normal bone growth and bone mineralization in mice.

Sachse G, Church C, Stewart M, Cater H, Teboul L, Cox RD, Ashcroft FM. Sachse G, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Mar;1864(3):843-850. doi: 10.1016/j.bbadis.2017.11.027. Epub 2017 Dec 2. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29203346 Free PMC article.

5

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.

Haythorne E, Rohm M, van de Bunt M, Brereton MF, Tarasov AI, Blacker TS, Sachse G, Silva Dos Santos M, Terron Exposito R, Davis S, Baba O, Fischer R, Duchen MR, Rorsman P, MacRae JI, Ashcroft FM. Haythorne E, et al. Among authors: sachse g. Nat Commun. 2019 Jun 6;10(1):2474. doi: 10.1038/s41467-019-10189-x. Nat Commun. 2019. PMID: 31171772 Free PMC article.

6

The KCNJ11-E23K Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion.

Sachse G, Haythorne E, Hill T, Proks P, Joynson R, Terrón-Expósito R, Bentley L, Tucker SJ, Cox RD, Ashcroft FM. Sachse G, et al. Diabetes. 2021 May;70(5):1145-1156. doi: 10.2337/db20-0691. Epub 2021 Feb 10. Diabetes. 2021. PMID: 33568422

7

Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice.

Sachse G, Haythorne E, Proks P, Stewart M, Cater H, Ellard S, Davies B, Ashcroft FM. Sachse G, et al. Wellcome Open Res. 2021 Mar 15;5:15. doi: 10.12688/wellcomeopenres.15529.2. eCollection 2020. Wellcome Open Res. 2021. PMID: 34368464 Free PMC article.

8

Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.

Haythorne E, Lloyd M, Walsby-Tickle J, Tarasov AI, Sandbrink J, Portillo I, Exposito RT, Sachse G, Cyranka M, Rohm M, Rorsman P, McCullagh J, Ashcroft FM. Haythorne E, et al. Among authors: sachse g. Nat Commun. 2022 Nov 14;13(1):6754. doi: 10.1038/s41467-022-34095-x. Nat Commun. 2022. PMID: 36376280 Free PMC article.

9

Correction to 'Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels'.

Proks P, Puljung MC, Vedovato N, Sachse G, Mulvaney R, Ashcroft FM. Proks P, et al. Among authors: sachse g. Philos Trans R Soc Lond B Biol Sci. 2016 Sep 5;371(1702):20160330. doi: 10.1098/rstb.2016.0330. Philos Trans R Soc Lond B Biol Sci. 2016. PMID: 27481794 Free PMC article. No abstract available.

10

Smooth muscle BK channel activity influences blood pressure independent of vascular tone in mice.

Sachse G, Faulhaber J, Seniuk A, Ehmke H, Pongs O. Sachse G, et al. J Physiol. 2014 Jun 15;592(12):2563-74. doi: 10.1113/jphysiol.2014.272880. Epub 2014 Mar 31. J Physiol. 2014. PMID: 24687584 Free PMC article.

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