Saikh KU - Search Results

1

Staphylococcal enterotoxin A induction of pro-inflammatory cytokines and lethality in mice is primarily dependent on MyD88.

Kissner TL, Cisney ED, Ulrich RG, Fernandez S, Saikh KU. Kissner TL, et al. Among authors: saikh ku. Immunology. 2010 Aug;130(4):516-26. doi: 10.1111/j.1365-2567.2010.03249.x. Epub 2010 May 3. Immunology. 2010. PMID: 20465563 Free PMC article.

2

Regulation of HLA-DR and co-stimulatory molecule expression on natural killer T cells by granulocyte-macrophage colony-stimulating factor.

Saikh KU, Kissner T, Ulrich RG. Saikh KU, et al. Immunology. 2002 Jul;106(3):363-72. doi: 10.1046/j.1365-2567.2002.01446.x. Immunology. 2002. PMID: 12100724 Free PMC article.

3

CD56+-T-cell responses to bacterial superantigens and immune recognition of attenuated vaccines.

Saikh KU, Dyas B, Kissner T, Ulrich RG. Saikh KU, et al. Clin Diagn Lab Immunol. 2003 Nov;10(6):1065-73. doi: 10.1128/cdli.10.6.1065-1073.2003. Clin Diagn Lab Immunol. 2003. PMID: 14607868 Free PMC article.

4

Human monocytes infected with Yersinia pestis express cell surface TLR9 and differentiate into dendritic cells.

Saikh KU, Kissner TL, Sultana A, Ruthel G, Ulrich RG. Saikh KU, et al. J Immunol. 2004 Dec 15;173(12):7426-34. doi: 10.4049/jimmunol.173.12.7426. J Immunol. 2004. PMID: 15585868

5

Interleukin-15 increases vaccine efficacy through a mechanism linked to dendritic cell maturation and enhanced antibody titers.

Saikh KU, Kissner TL, Nystrom S, Ruthel G, Ulrich RG. Saikh KU, et al. Clin Vaccine Immunol. 2008 Jan;15(1):131-7. doi: 10.1128/CVI.00320-07. Epub 2007 Nov 28. Clin Vaccine Immunol. 2008. PMID: 18045883 Free PMC article.

6

MyD88-dependent pro-inflammatory cytokine response contributes to lethal toxicity of staphylococcal enterotoxin B in mice.

Kissner TL, Ruthel G, Cisney ED, Ulrich RG, Fernandez S, Saikh KU. Kissner TL, et al. Among authors: saikh ku. Innate Immun. 2011 Oct;17(5):451-62. doi: 10.1177/1753425910374092. Epub 2010 Aug 10. Innate Immun. 2011. PMID: 20699281 Free article.

7

Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules.

Kissner TL, Ruthel G, Alam S, Ulrich RG, Fernandez S, Saikh KU. Kissner TL, et al. Among authors: saikh ku. PLoS One. 2011 Jan 20;6(1):e15985. doi: 10.1371/journal.pone.0015985. PLoS One. 2011. PMID: 21283748 Free PMC article.

8

A small molecule that mimics the BB-loop in the Toll interleukin-1 (IL-1) receptor domain of MyD88 attenuates staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in mice.

Kissner TL, Moisan L, Mann E, Alam S, Ruthel G, Ulrich RG, Rebek M, Rebek J Jr, Saikh KU. Kissner TL, et al. Among authors: saikh ku. J Biol Chem. 2011 Sep 9;286(36):31385-96. doi: 10.1074/jbc.M110.204982. Epub 2011 Jun 21. J Biol Chem. 2011. PMID: 21693701 Free PMC article.

9

Therapeutic inhibition of pro-inflammatory signaling and toxicity to staphylococcal enterotoxin B by a synthetic dimeric BB-loop mimetic of MyD88.

Kissner TL, Ruthel G, Alam S, Mann E, Ajami D, Rebek M, Larkin E, Fernandez S, Ulrich RG, Ping S, Waugh DS, Rebek J Jr, Saikh KU. Kissner TL, et al. Among authors: saikh ku. PLoS One. 2012;7(7):e40773. doi: 10.1371/journal.pone.0040773. Epub 2012 Jul 27. PLoS One. 2012. PMID: 22848400 Free PMC article. Clinical Trial.

10

Structure-Based Design and Synthesis of a Small Molecule that Exhibits Anti-inflammatory Activity by Inhibition of MyD88-mediated Signaling to Bacterial Toxin Exposure.

Alam S, Javor S, Degardin M, Ajami D, Rebek M, Kissner TL, Waag DM, Rebek J Jr, Saikh KU. Alam S, et al. Among authors: saikh ku. Chem Biol Drug Des. 2015 Aug;86(2):200-9. doi: 10.1111/cbdd.12477. Epub 2014 Dec 8. Chem Biol Drug Des. 2015. PMID: 25393063

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