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RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8.
Imanishi T, Unno M, Yoneda N, Motomura Y, Mochizuki M, Sasaki T, Pasparakis M, Saito T. Imanishi T, et al. Among authors: saito t. Sci Adv. 2023 Jan 25;9(4):eadd6097. doi: 10.1126/sciadv.add6097. Epub 2023 Jan 25. Sci Adv. 2023. PMID: 36696505 Free PMC article.
A critical role for the innate immune signaling molecule IRAK-4 in T cell activation.
Suzuki N, Suzuki S, Millar DG, Unno M, Hara H, Calzascia T, Yamasaki S, Yokosuka T, Chen NJ, Elford AR, Suzuki J, Takeuchi A, Mirtsos C, Bouchard D, Ohashi PS, Yeh WC, Saito T. Suzuki N, et al. Among authors: saito t. Science. 2006 Mar 31;311(5769):1927-32. doi: 10.1126/science.1124256. Science. 2006. PMID: 16574867
Cutting edge: TLR2 directly triggers Th1 effector functions.
Imanishi T, Hara H, Suzuki S, Suzuki N, Akira S, Saito T. Imanishi T, et al. Among authors: saito t. J Immunol. 2007 Jun 1;178(11):6715-9. doi: 10.4049/jimmunol.178.11.6715. J Immunol. 2007. PMID: 17513716
Nucleic acid sensing by T cells initiates Th2 cell differentiation.
Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T. Imanishi T, et al. Among authors: saito t. Nat Commun. 2014 Apr 10;5:3566. doi: 10.1038/ncomms4566. Nat Commun. 2014. PMID: 24717539 Free article.
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