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MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation.
Craig JE, Miller JN, Rayavarapu RR, Hong Z, Bulut GB, Zhuang W, Sakurada SM, Temirov J, Low JA, Chen T, Pruett-Miller SM, Huang LJ, Potts MB. Craig JE, et al. Among authors: sakurada sm. Cell Death Discov. 2020 Oct 20;6:107. doi: 10.1038/s41420-020-00342-7. eCollection 2020. Cell Death Discov. 2020. PMID: 33101709 Free PMC article.
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor.
Jablonowski C, Quarni W, Singh S, Tan H, Bostanthirige DH, Jin H, Fang J, Chang TC, Finkelstein D, Cho JH, Hu D, Pagala V, Sakurada SM, Pruett-Miller SM, Wang R, Murphy A, Freeman K, Peng J, Davidoff AM, Wu G, Yang J. Jablonowski C, et al. Among authors: sakurada sm. bioRxiv [Preprint]. 2023 Nov 20:2023.06.26.546606. doi: 10.1101/2023.06.26.546606. bioRxiv. 2023. PMID: 37425900 Free PMC article. Updated. Preprint.
A CRISPR/Cas9 engineered MplS504N mouse model recapitulates human myelofibrosis.
Adriaanse FRS, Kamens JL, Vogel P, Sakurada SM, Pruett-Miller SM, Stam RW, Michel Zwaan C, Gruber TA. Adriaanse FRS, et al. Among authors: sakurada sm. Leukemia. 2022 Oct;36(10):2535-2538. doi: 10.1038/s41375-022-01684-0. Epub 2022 Aug 23. Leukemia. 2022. PMID: 35999261 No abstract available.
FANCL supports Parkin-mediated mitophagy in a ubiquitin ligase-independent manner.
Beesetti S, Sirasanagandla S, Sakurada SM, Pruett-Miller SM, Sumpter R Jr, Levine B, Potts MB. Beesetti S, et al. Among authors: sakurada sm. Biochim Biophys Acta Mol Basis Dis. 2022 Sep 1;1868(9):166453. doi: 10.1016/j.bbadis.2022.166453. Epub 2022 May 26. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35644338 Free PMC article.
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor.
Jablonowski CM, Quarni W, Singh S, Tan H, Bostanthirige DH, Jin H, Fang J, Chang TC, Finkelstein D, Cho JH, Hu D, Pagala V, Sakurada SM, Pruett-Miller SM, Wang R, Murphy A, Freeman K, Peng J, Davidoff AM, Wu G, Yang J. Jablonowski CM, et al. Among authors: sakurada sm. Elife. 2024 Mar 15;12:RP90993. doi: 10.7554/eLife.90993. Elife. 2024. PMID: 38488852 Free PMC article.
Cleavage activates dispatched for Sonic Hedgehog ligand release.
Stewart DP, Marada S, Bodeen WJ, Truong A, Sakurada SM, Pandit T, Pruett-Miller SM, Ogden SK. Stewart DP, et al. Among authors: sakurada sm. Elife. 2018 Jan 23;7:e31678. doi: 10.7554/eLife.31678. Elife. 2018. PMID: 29359685 Free PMC article.
Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice.
Eom TY, Han SB, Kim J, Blundon JA, Wang YD, Yu J, Anderson K, Kaminski DB, Sakurada SM, Pruett-Miller SM, Horner L, Wagner B, Robinson CG, Eicholtz M, Rose DC, Zakharenko SS. Eom TY, et al. Among authors: sakurada sm. Nat Commun. 2020 Feb 14;11(1):912. doi: 10.1038/s41467-020-14628-y. Nat Commun. 2020. PMID: 32060266 Free PMC article.
The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51.
Park JM, Yang SW, Zhuang W, Bera AK, Liu Y, Gurbani D, von Hoyningen-Huene SJ, Sakurada SM, Gan H, Pruett-Miller SM, Westover KD, Potts MB. Park JM, et al. Among authors: sakurada sm. PLoS Biol. 2021 Jun 2;19(6):e3001281. doi: 10.1371/journal.pbio.3001281. eCollection 2021 Jun. PLoS Biol. 2021. PMID: 34077419 Free PMC article.