Salvesen G - Search Results

1

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity.

Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B, Glinsky G, Scudiero D, Sausville E, Salvesen G, Nefzi A, Ostresh JM, Houghten RA, Reed JC. Schimmer AD, et al. Among authors: salvesen g. Cancer Cell. 2004 Jan;5(1):25-35. doi: 10.1016/s1535-6108(03)00332-5. Cancer Cell. 2004. PMID: 14749124 Free article.

2

X-linked IAP is a direct inhibitor of cell-death proteases.

Deveraux QL, Takahashi R, Salvesen GS, Reed JC. Deveraux QL, et al. Among authors: salvesen gs. Nature. 1997 Jul 17;388(6639):300-4. doi: 10.1038/40901. Nature. 1997. PMID: 9230442

3

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases.

Cardone MH, Salvesen GS, Widmann C, Johnson G, Frisch SM. Cardone MH, et al. Among authors: salvesen gs. Cell. 1997 Jul 25;90(2):315-23. doi: 10.1016/s0092-8674(00)80339-6. Cell. 1997. PMID: 9244305 Free article.

4

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis.

Caulín C, Salvesen GS, Oshima RG. Caulín C, et al. Among authors: salvesen gs. J Cell Biol. 1997 Sep 22;138(6):1379-94. doi: 10.1083/jcb.138.6.1379. J Cell Biol. 1997. PMID: 9298992 Free PMC article.

5

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases.

Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. Roy N, et al. Among authors: salvesen gs. EMBO J. 1997 Dec 1;16(23):6914-25. doi: 10.1093/emboj/16.23.6914. EMBO J. 1997. PMID: 9384571 Free PMC article.

6

Caspases: intracellular signaling by proteolysis.

Salvesen GS, Dixit VM. Salvesen GS, et al. Cell. 1997 Nov 14;91(4):443-6. doi: 10.1016/s0092-8674(00)80430-4. Cell. 1997. PMID: 9390553 Free article. Review. No abstract available.

7

Granzyme release and caspase activation in activated human T-lymphocytes.

Zapata JM, Takahashi R, Salvesen GS, Reed JC. Zapata JM, et al. Among authors: salvesen gs. J Biol Chem. 1998 Mar 20;273(12):6916-20. doi: 10.1074/jbc.273.12.6916. J Biol Chem. 1998. PMID: 9506996 Free article.

8

A single BIR domain of XIAP sufficient for inhibiting caspases.

Takahashi R, Deveraux Q, Tamm I, Welsh K, Assa-Munt N, Salvesen GS, Reed JC. Takahashi R, et al. Among authors: salvesen gs. J Biol Chem. 1998 Apr 3;273(14):7787-90. doi: 10.1074/jbc.273.14.7787. J Biol Chem. 1998. PMID: 9525868 Free article.

9

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.

Deveraux QL, Roy N, Stennicke HR, Van Arsdale T, Zhou Q, Srinivasula SM, Alnemri ES, Salvesen GS, Reed JC. Deveraux QL, et al. Among authors: salvesen gs. EMBO J. 1998 Apr 15;17(8):2215-23. doi: 10.1093/emboj/17.8.2215. EMBO J. 1998. PMID: 9545235 Free PMC article.

10

Pro-caspase-3 is a major physiologic target of caspase-8.

Stennicke HR, Jürgensmeier JM, Shin H, Deveraux Q, Wolf BB, Yang X, Zhou Q, Ellerby HM, Ellerby LM, Bredesen D, Green DR, Reed JC, Froelich CJ, Salvesen GS. Stennicke HR, et al. Among authors: salvesen gs. J Biol Chem. 1998 Oct 16;273(42):27084-90. doi: 10.1074/jbc.273.42.27084. J Biol Chem. 1998. PMID: 9765224 Free article.

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