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SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response.
Bland P, Saville H, Wai PT, Curnow L, Muirhead G, Nieminuszczy J, Ravindran N, John MB, Hedayat S, Barker HE, Wright J, Yu L, Mavrommati I, Read A, Peck B, Allen M, Gazinska P, Pemberton HN, Gulati A, Nash S, Noor F, Guppy N, Roxanis I, Pratt G, Oldreive C, Stankovic T, Barlow S, Kalirai H, Coupland SE, Broderick R, Alsafadi S, Houy A, Stern MH, Pettit S, Choudhary JS, Haider S, Niedzwiedz W, Lord CJ, Natrajan R. Bland P, et al. Among authors: barlow s. Nat Genet. 2023 Aug;55(8):1311-1323. doi: 10.1038/s41588-023-01460-5. Epub 2023 Jul 31. Nat Genet. 2023. PMID: 37524790 Free PMC article.
Investigating the Role of DUSP4 in Uveal Melanoma.
Aughton K, Sabat-Pospiech D, Barlow S, Coupland SE, Kalirai H. Aughton K, et al. Among authors: barlow s. Transl Vis Sci Technol. 2022 Dec 1;11(12):13. doi: 10.1167/tvst.11.12.13. Transl Vis Sci Technol. 2022. PMID: 36576731 Free PMC article.