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MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity.
Cell Rep. 2021 Mar 2;34(9):108808. doi: 10.1016/j.celrep.2021.108808.
Cell Rep. 2021.
PMID: 33657372
Free PMC article.
USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors.
Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, Parmar K, Yusufzai T, Zheng N, D'Andrea AD.
Lim KS, et al. Among authors: sambel la.
Mol Cell. 2018 Dec 20;72(6):925-941.e4. doi: 10.1016/j.molcel.2018.10.045.
Mol Cell. 2018.
PMID: 30576655
Free PMC article.
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The CHK1 Inhibitor Prexasertib Exhibits Monotherapy Activity in High-Grade Serous Ovarian Cancer Models and Sensitizes to PARP Inhibition.
Parmar K, Kochupurakkal BS, Lazaro JB, Wang ZC, Palakurthi S, Kirschmeier PT, Yang C, Sambel LA, Färkkilä A, Reznichenko E, Reavis HD, Dunn CE, Zou L, Do KT, Konstantinopoulos PA, Matulonis UA, Liu JF, D'Andrea AD, Shapiro GI.
Parmar K, et al. Among authors: sambel la.
Clin Cancer Res. 2019 Oct 15;25(20):6127-6140. doi: 10.1158/1078-0432.CCR-19-0448. Epub 2019 Aug 13.
Clin Cancer Res. 2019.
PMID: 31409614
Free PMC article.
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MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia.
Rodríguez A, Zhang K, Färkkilä A, Filiatrault J, Yang C, Velázquez M, Furutani E, Goldman DC, García de Teresa B, Garza-Mayén G, McQueen K, Sambel LA, Molina B, Torres L, González M, Vadillo E, Pelayo R, Fleming WH, Grompe M, Shimamura A, Hautaniemi S, Greenberger J, Frías S, Parmar K, D'Andrea AD.
Rodríguez A, et al. Among authors: sambel la.
Cell Stem Cell. 2021 Jan 7;28(1):33-47.e8. doi: 10.1016/j.stem.2020.09.004. Epub 2020 Sep 29.
Cell Stem Cell. 2021.
PMID: 32997960
Free PMC article.
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Inhibition of TGFβ1 and TGFβ3 promotes hematopoiesis in Fanconi anemia.
Rodríguez A, Yang C, Furutani E, García de Teresa B, Velázquez M, Filiatrault J, Sambel LA, Phan T, Flores-Guzmán P, Sánchez S, Monsiváis Orozco A, Mayani H, Bolukbasi OV, Färkkilä A, Epperly M, Greenberger J, Shimamura A, Frías S, Grompe M, Parmar K, D'Andrea AD.
Rodríguez A, et al. Among authors: sambel la.
Exp Hematol. 2021 Jan;93:70-84.e4. doi: 10.1016/j.exphem.2020.11.002. Epub 2020 Nov 7.
Exp Hematol. 2021.
PMID: 33166613
Free PMC article.
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TGFβ pathway is required for viable gestation of Fanconi anemia embryos.
Rodríguez A, Epperly M, Filiatrault J, Velázquez M, Yang C, McQueen K, Sambel LA, Nguyen H, Iyer DR, Juárez U, Ayala-Zambrano C, Martignetti DB, Frías S, Fisher R, Parmar K, Greenberger JS, D'Andrea AD.
Rodríguez A, et al. Among authors: sambel la.
PLoS Genet. 2022 Nov 28;18(11):e1010459. doi: 10.1371/journal.pgen.1010459. eCollection 2022 Nov.
PLoS Genet. 2022.
PMID: 36441774
Free PMC article.
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E6AP/UBE3A catalyzes encephalomyocarditis virus 3C protease polyubiquitylation and promotes its concentration reduction in virus-infected cells.
Carmody M, Notarianni TP, Sambel LA, Walsh SJ, Burke JM, Armstrong JL, Lawson TG.
Carmody M, et al. Among authors: sambel la.
Biochem Biophys Res Commun. 2017 Dec 9;494(1-2):63-69. doi: 10.1016/j.bbrc.2017.10.084. Epub 2017 Oct 18.
Biochem Biophys Res Commun. 2017.
PMID: 29054411
Free PMC article.
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Single-Molecule Imaging Reveals the Mechanism of Bidirectional Replication Initiation in Metazoa.
Terui R, Berger S, Sambel L, Song D, Chistol G.
Terui R, et al. Among authors: sambel l.
bioRxiv [Preprint]. 2024 Mar 28:2024.03.28.587265. doi: 10.1101/2024.03.28.587265.
bioRxiv. 2024.
PMID: 38585807
Free PMC article.
Preprint.
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