Samulski RJ - Search Results

1

AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.

Elsworth JD, Redmond DE Jr, Leranth C, Bjugstad KB, Sladek JR Jr, Collier TJ, Foti SB, Samulski RJ, Vives KP, Roth RH. Elsworth JD, et al. Among authors: samulski rj. Exp Neurol. 2008 May;211(1):252-8. doi: 10.1016/j.expneurol.2008.01.026. Epub 2008 Feb 15. Exp Neurol. 2008. PMID: 18346734 Free PMC article.

2

Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model.

Redmond DE Jr, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR Jr. Redmond DE Jr, et al. Among authors: samulski rj. Mol Ther. 2013 Dec;21(12):2160-8. doi: 10.1038/mt.2013.180. Epub 2013 Aug 5. Mol Ther. 2013. PMID: 23913185 Free PMC article.

3

Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain.

Markakis EA, Vives KP, Bober J, Leichtle S, Leranth C, Beecham J, Elsworth JD, Roth RH, Samulski RJ, Redmond DE Jr. Markakis EA, et al. Among authors: samulski rj. Mol Ther. 2010 Mar;18(3):588-93. doi: 10.1038/mt.2009.286. Epub 2009 Dec 15. Mol Ther. 2010. PMID: 20010918 Free PMC article.

4

Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target.

Wakeman DR, Redmond DE Jr, Dodiya HB, Sladek JR Jr, Leranth C, Teng YD, Samulski RJ, Snyder EY. Wakeman DR, et al. Among authors: samulski rj. Stem Cells Transl Med. 2014 Jun;3(6):692-701. doi: 10.5966/sctm.2013-0208. Epub 2014 Apr 17. Stem Cells Transl Med. 2014. PMID: 24744393 Free PMC article.

5

Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.

Redmond DE Jr, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P, Sladek JR Jr. Redmond DE Jr, et al. Among authors: samulski rj. J Comp Neurol. 2009 Jul 1;515(1):31-40. doi: 10.1002/cne.22028. J Comp Neurol. 2009. PMID: 19399891 Free PMC article.

6

In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector.

During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR Jr, O'Malley KL, Redmond DE Jr. During MJ, et al. Among authors: samulski rj. Gene Ther. 1998 Jun;5(6):820-7. doi: 10.1038/sj.gt.3300650. Gene Ther. 1998. PMID: 9747462

7

Delivering multiple gene products in the brain from a single adeno-associated virus vector.

Foti SB, Samulski RJ, McCown TJ. Foti SB, et al. Among authors: samulski rj. Gene Ther. 2009 Nov;16(11):1314-9. doi: 10.1038/gt.2009.106. Epub 2009 Sep 3. Gene Ther. 2009. PMID: 19727140 Free PMC article.

8

Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo.

Foti S, Haberman RP, Samulski RJ, McCown TJ. Foti S, et al. Among authors: samulski rj. Gene Ther. 2007 Nov;14(21):1534-6. doi: 10.1038/sj.gt.3303013. Epub 2007 Aug 23. Gene Ther. 2007. PMID: 17713567 Free PMC article.

9

Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors.

Gray SJ, Foti SB, Schwartz JW, Bachaboina L, Taylor-Blake B, Coleman J, Ehlers MD, Zylka MJ, McCown TJ, Samulski RJ. Gray SJ, et al. Among authors: samulski rj. Hum Gene Ther. 2011 Sep;22(9):1143-53. doi: 10.1089/hum.2010.245. Epub 2011 Jun 1. Hum Gene Ther. 2011. PMID: 21476867 Free PMC article.

10

Optimization of scAAVIL-1ra In Vitro and In Vivo to Deliver High Levels of Therapeutic Protein for Treatment of Osteoarthritis.

Goodrich LR, Phillips JN, McIlwraith CW, Foti SB, Grieger JC, Gray SJ, Samulski RJ. Goodrich LR, et al. Among authors: samulski rj. Mol Ther Nucleic Acids. 2013 Feb 5;2(2):e70. doi: 10.1038/mtna.2012.61. Mol Ther Nucleic Acids. 2013. PMID: 23385523 Free PMC article.

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