Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

2,679 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.
Wu K, Huynh KQ, Lu I, Moustakim M, Miao H, Yu C, Haeusgen MJ, Hopkins BD, Huang L, Zheng N, Sanchez R, DeVita RJ, Pan ZQ. Wu K, et al. Among authors: sanchez r. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2007328118. doi: 10.1073/pnas.2007328118. Proc Natl Acad Sci U S A. 2021. PMID: 33602808 Free PMC article.
Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination.
Chong RA, Wu K, Spratt DE, Yang Y, Lee C, Nayak J, Xu M, Elkholi R, Tappin I, Li J, Hurwitz J, Brown BD, Chipuk JE, Chen ZJ, Sanchez R, Shaw GS, Huang L, Pan ZQ. Chong RA, et al. Among authors: sanchez r. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8434-9. doi: 10.1073/pnas.1407849111. Epub 2014 May 27. Proc Natl Acad Sci U S A. 2014. PMID: 24912152 Free PMC article.
Suramin inhibits cullin-RING E3 ubiquitin ligases.
Wu K, Chong RA, Yu Q, Bai J, Spratt DE, Ching K, Lee C, Miao H, Tappin I, Hurwitz J, Zheng N, Shaw GS, Sun Y, Felsenfeld DP, Sanchez R, Zheng JN, Pan ZQ. Wu K, et al. Among authors: sanchez r. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2011-8. doi: 10.1073/pnas.1601089113. Epub 2016 Mar 21. Proc Natl Acad Sci U S A. 2016. PMID: 27001857 Free PMC article.
Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex.
Leandro J, Khamrui S, Wang H, Suebsuwong C, Nemeria NS, Huynh K, Moustakim M, Secor C, Wang M, Dodatko T, Stauffer B, Wilson CG, Yu C, Arkin MR, Jordan F, Sanchez R, DeVita RJ, Lazarus MB, Houten SM. Leandro J, et al. Among authors: sanchez r. ACS Chem Biol. 2020 Aug 21;15(8):2041-2047. doi: 10.1021/acschembio.0c00114. Epub 2020 Jul 9. ACS Chem Biol. 2020. PMID: 32633484 Free PMC article.
Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor.
Kumar K, Wang P, Wilson J, Zlatanic V, Berrouet C, Khamrui S, Secor C, Swartz EA, Lazarus M, Sanchez R, Stewart AF, Garcia-Ocana A, DeVita RJ. Kumar K, et al. Among authors: sanchez r. J Med Chem. 2020 Mar 26;63(6):2986-3003. doi: 10.1021/acs.jmedchem.9b01379. Epub 2020 Feb 19. J Med Chem. 2020. PMID: 32003560 Free PMC article.
2,679 results