Sandegren A - Search Results

1

Amyloid beta-peptide aggregation. What does it result in and how can it be prevented?

Nerelius C, Johansson J, Sandegren A. Nerelius C, et al. Among authors: sandegren a. Front Biosci (Landmark Ed). 2009 Jan 1;14(5):1716-29. doi: 10.2741/3335. Front Biosci (Landmark Ed). 2009. PMID: 19273157 Free article.

2

Alpha-helix targeting reduces amyloid-beta peptide toxicity.

Nerelius C, Sandegren A, Sargsyan H, Raunak R, Leijonmarck H, Chatterjee U, Fisahn A, Imarisio S, Lomas DA, Crowther DC, Strömberg R, Johansson J. Nerelius C, et al. Among authors: sandegren a. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9191-6. doi: 10.1073/pnas.0810364106. Epub 2009 May 20. Proc Natl Acad Sci U S A. 2009. PMID: 19458258 Free PMC article.

3

Poly-N-methylated amyloid beta-peptide (Abeta) C-terminal fragments reduce Abeta toxicity in vitro and in Drosophila melanogaster.

Pratim Bose P, Chatterjee U, Nerelius C, Govender T, Norström T, Gogoll A, Sandegren A, Göthelid E, Johansson J, Arvidsson PI. Pratim Bose P, et al. Among authors: sandegren a. J Med Chem. 2009 Dec 24;52(24):8002-9. doi: 10.1021/jm901092h. J Med Chem. 2009. PMID: 19908889

4

Co-culture platform for tuning of cancer receptor density allows for evaluation of bispecific immune cell engagers.

Mebrahtu A, Aniander G, Mega A, Moradi Barzadd M, Berndt Thalén N, Gudmundsdotter L, Backström Rydin E, Sandegren A, Frejd FY, Rockberg J. Mebrahtu A, et al. Among authors: sandegren a. N Biotechnol. 2024 Mar 25;79:120-126. doi: 10.1016/j.nbt.2023.12.012. Epub 2023 Dec 28. N Biotechnol. 2024. PMID: 38159596 Free article.

5

Tuning of CHO secretional machinery improve activity of secreted therapeutic sulfatase 150-fold.

Thalén NB, Barzadd MM, Lundqvist M, Rodhe J, Andersson M, Bidkhori G, Possner D, Su C, Nilsson J, Eisenhut P, Malm M, Karlsson A, Vestin J, Forsberg J, Nordling E, Mardinoglu A, Volk AL, Sandegren A, Rockberg J. Thalén NB, et al. Among authors: sandegren a. Metab Eng. 2024 Jan;81:157-166. doi: 10.1016/j.ymben.2023.12.003. Epub 2023 Dec 9. Metab Eng. 2024. PMID: 38081506 Free article.

6

A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activation.

Mega A, Mebrahtu A, Aniander G, Ryer E, Sköld A, Sandegren A, Backström Rydin E, Rockberg J, Östman A, Frejd FY. Mega A, et al. Among authors: sandegren a. MAbs. 2023 Jan-Dec;15(1):2223750. doi: 10.1080/19420862.2023.2223750. MAbs. 2023. PMID: 37332119 Free PMC article.

7

Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules.

Gast V, Sandegren A, Dunås F, Ekblad S, Güler R, Thorén S, Tous Mohedano M, Molin M, Engqvist MKM, Siewers V. Gast V, et al. Among authors: sandegren a. Microb Cell Fact. 2022 Mar 9;21(1):36. doi: 10.1186/s12934-022-01761-0. Microb Cell Fact. 2022. PMID: 35264156 Free PMC article.

8

Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome.

Hendrikse NM, Sandegren A, Andersson T, Blomqvist J, Makower Å, Possner D, Su C, Thalén N, Tjernberg A, Westermark U, Rockberg J, Svensson Gelius S, Syrén PO, Nordling E. Hendrikse NM, et al. Among authors: sandegren a. iScience. 2021 Feb 6;24(3):102154. doi: 10.1016/j.isci.2021.102154. eCollection 2021 Mar 19. iScience. 2021. PMID: 33665572 Free PMC article.

9

Systematic use of synthetic 5'-UTR RNA structures to tune protein translation improves yield and quality of complex proteins in mammalian cell factories.

Eisenhut P, Mebrahtu A, Moradi Barzadd M, Thalén N, Klanert G, Weinguny M, Sandegren A, Su C, Hatton D, Borth N, Rockberg J. Eisenhut P, et al. Among authors: sandegren a. Nucleic Acids Res. 2020 Nov 18;48(20):e119. doi: 10.1093/nar/gkaa847. Nucleic Acids Res. 2020. PMID: 33051690 Free PMC article.

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