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Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*.
Jangra S, De Vrieze J, Choi A, Rathnasinghe R, Laghlali G, Uvyn A, Van Herck S, Nuhn L, Deswarte K, Zhong Z, Sanders NN, Lienenklaus S, David SA, Strohmeier S, Amanat F, Krammer F, Hammad H, Lambrecht BN, Coughlan L, García-Sastre A, De Geest BG, Schotsaert M. Jangra S, et al. Among authors: sanders nn. Angew Chem Int Ed Engl. 2021 Apr 19;60(17):9467-9473. doi: 10.1002/anie.202015362. Epub 2021 Mar 11. Angew Chem Int Ed Engl. 2021. PMID: 33464672 Free PMC article.
Release mechanisms for polyelectrolyte capsules.
De Geest BG, Sanders NN, Sukhorukov GB, Demeester J, De Smedt SC. De Geest BG, et al. Among authors: sanders nn. Chem Soc Rev. 2007 Apr;36(4):636-49. doi: 10.1039/b600460c. Epub 2006 Oct 13. Chem Soc Rev. 2007. PMID: 17387411 Review.
Topical imiquimod yields systemic effects due to unintended oral uptake.
Grine L, Steeland S, Van Ryckeghem S, Ballegeer M, Lienenklaus S, Weiss S, Sanders NN, Vandenbroucke RE, Libert C. Grine L, et al. Among authors: sanders nn. Sci Rep. 2016 Jan 28;6:20134. doi: 10.1038/srep20134. Sci Rep. 2016. PMID: 26818707 Free PMC article.
Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists.
De Vrieze J, Louage B, Deswarte K, Zhong Z, De Coen R, Van Herck S, Nuhn L, Kaas Frich C, Zelikin AN, Lienenklaus S, Sanders NN, Lambrecht BN, David SA, De Geest BG. De Vrieze J, et al. Among authors: sanders nn. Angew Chem Int Ed Engl. 2019 Oct 21;58(43):15390-15395. doi: 10.1002/anie.201905687. Epub 2019 Sep 12. Angew Chem Int Ed Engl. 2019. PMID: 31397948
138 results