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Page 1
Emotional and behavioural aspects of Rett syndrome.
Sansom D, Krishnan VH, Corbett J, Kerr A. Sansom D, et al. Dev Med Child Neurol. 1993 Apr;35(4):340-5. doi: 10.1111/j.1469-8749.1993.tb11646.x. Dev Med Child Neurol. 1993. PMID: 8335149
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies.
Lax BM, Palmeri JR, Lutz EA, Sheen A, Stinson JA, Duhamel L, Santollani L, Kennedy A, Rothschilds AM, Spranger S, Sansom DM, Wittrup KD. Lax BM, et al. Among authors: sansom dm. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2300895120. doi: 10.1073/pnas.2300895120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487077 Free PMC article.
Therapeutic gene editing of T cells to correct CTLA-4 insufficiency.
Fox TA, Houghton BC, Petersone L, Waters E, Edner NM, McKenna A, Preham O, Hinze C, Williams C, de Albuquerque AS, Kennedy A, Pesenacker AM, Genovese P, Walker LSK, Burns SO, Sansom DM, Booth C, Morris EC. Fox TA, et al. Among authors: sansom dm. Sci Transl Med. 2022 Oct 26;14(668):eabn5811. doi: 10.1126/scitranslmed.abn5811. Epub 2022 Oct 26. Sci Transl Med. 2022. PMID: 36288278
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation.
Kennedy A, Waters E, Rowshanravan B, Hinze C, Williams C, Janman D, Fox TA, Booth C, Pesenacker AM, Halliday N, Soskic B, Kaur S, Qureshi OS, Morris EC, Ikemizu S, Paluch C, Huo J, Davis SJ, Boucrot E, Walker LSK, Sansom DM. Kennedy A, et al. Among authors: sansom dm. Nat Immunol. 2022 Sep;23(9):1365-1378. doi: 10.1038/s41590-022-01289-w. Epub 2022 Aug 23. Nat Immunol. 2022. PMID: 35999394 Free PMC article.
Regulation of CTLA-4 recycling by LRBA and Rab11.
Janman D, Hinze C, Kennedy A, Halliday N, Waters E, Williams C, Rowshanravan B, Hou TZ, Minogue S, Qureshi OS, Sansom DM. Janman D, et al. Among authors: sansom dm. Immunology. 2021 Sep;164(1):106-119. doi: 10.1111/imm.13343. Epub 2021 Jun 6. Immunology. 2021. PMID: 33960403 Free PMC article.
117 results