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Tumor suppression by Spinophilin.
Santamaría D, Malumbres M. Santamaría D, et al. Cell Cycle. 2011 Sep 1;10(17):2831-2. Epub 2011 Sep 1. Cell Cycle. 2011. PMID: 21869595 No abstract available.
Functional reprogramming of polyploidization in megakaryocytes.
Trakala M, Rodríguez-Acebes S, Maroto M, Symonds CE, Santamaría D, Ortega S, Barbacid M, Méndez J, Malumbres M. Trakala M, et al. Among authors: santamaria d. Dev Cell. 2015 Jan 26;32(2):155-67. doi: 10.1016/j.devcel.2014.12.015. Dev Cell. 2015. PMID: 25625205 Free article.
Cdk1 is sufficient to drive the mammalian cell cycle.
Santamaría D, Barrière C, Cerqueira A, Hunt S, Tardy C, Newton K, Cáceres JF, Dubus P, Malumbres M, Barbacid M. Santamaría D, et al. Nature. 2007 Aug 16;448(7155):811-5. doi: 10.1038/nature06046. Nature. 2007. PMID: 17700700
Mice thrive without Cdk4 and Cdk2.
Barrière C, Santamaría D, Cerqueira A, Galán J, Martín A, Ortega S, Malumbres M, Dubus P, Barbacid M. Barrière C, et al. Among authors: santamaria d. Mol Oncol. 2007 Jun;1(1):72-83. doi: 10.1016/j.molonc.2007.03.001. Epub 2007 Mar 14. Mol Oncol. 2007. PMID: 19383288 Free PMC article.
Squamous differentiation requires G2/mitosis slippage to avoid apoptosis.
Sanz-Gómez N, de Pedro I, Ortigosa B, Santamaría D, Malumbres M, de Cárcer G, Gandarillas A. Sanz-Gómez N, et al. Among authors: santamaria d. Cell Death Differ. 2020 Aug;27(8):2451-2467. doi: 10.1038/s41418-020-0515-2. Epub 2020 Feb 20. Cell Death Differ. 2020. PMID: 32080348 Free PMC article.
RAF1 kinase activity is dispensable for KRAS/p53 mutant lung tumor progression.
Sanclemente M, Nieto P, Garcia-Alonso S, Fernández-García F, Esteban-Burgos L, Guerra C, Drosten M, Caleiras E, Martinez-Torrecuadrada J, Santamaría D, Musteanu M, Barbacid M. Sanclemente M, et al. Among authors: santamaria d. Cancer Cell. 2021 Mar 8;39(3):294-296. doi: 10.1016/j.ccell.2021.01.008. Epub 2021 Jan 28. Cancer Cell. 2021. PMID: 33513349 Free article. No abstract available.
Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas.
Esteban-Burgos L, Wang H, Nieto P, Zheng J, Blanco-Aparicio C, Varela C, Gómez-López G, Fernández-García F, Sanclemente M, Guerra C, Drosten M, Galán J, Caleiras E, Martínez-Torrecuadrada J, Fajas L, Peng SB, Santamaría D, Musteanu M, Barbacid M. Esteban-Burgos L, et al. Among authors: santamaria d. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24415-24426. doi: 10.1073/pnas.2002520117. Epub 2020 Sep 10. Proc Natl Acad Sci U S A. 2020. PMID: 32913049 Free PMC article.
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