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Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination.
Schvartzman JM, Forsyth G, Walch H, Chatila W, Taglialatela A, Lee BJ, Zhu X, Gershik S, Cimino FV, Santella A, Menghrajani K, Ciccia A, Koche R, Sánchez-Vega F, Zha S, Thompson CB. Schvartzman JM, et al. Among authors: santella a. Mol Cell. 2023 Jul 6;83(13):2347-2356.e8. doi: 10.1016/j.molcel.2023.05.026. Epub 2023 Jun 12. Mol Cell. 2023. PMID: 37311462
Automated Cell Lineage Reconstruction using Label-Free 4D Microscopy.
Waliman M, Johnson RL, Natesan G, Tan S, Santella A, Hong RL, Shah PK. Waliman M, et al. Among authors: santella a. bioRxiv [Preprint]. 2024 Jan 22:2024.01.20.576449. doi: 10.1101/2024.01.20.576449. bioRxiv. 2024. PMID: 38328064 Free PMC article. Preprint.
In vivo tumor immune microenvironment phenotypes correlate with inflammation and vasculature to predict immunotherapy response.
Sahu A, Kose K, Kraehenbuehl L, Byers C, Holland A, Tembo T, Santella A, Alfonso A, Li M, Cordova M, Gill M, Fox C, Gonzalez S, Kumar P, Wang AW, Kurtansky N, Chandrani P, Yin S, Mehta P, Navarrete-Dechent C, Peterson G, King K, Dusza S, Yang N, Liu S, Phillips W, Guitera P, Rossi A, Halpern A, Deng L, Pulitzer M, Marghoob A, Chen CJ, Merghoub T, Rajadhyaksha M. Sahu A, et al. Among authors: santella a. Nat Commun. 2022 Sep 9;13(1):5312. doi: 10.1038/s41467-022-32738-7. Nat Commun. 2022. PMID: 36085288 Free PMC article.
70 results