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Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy.
Front Physiol. 2019 Oct 1;10:1258. doi: 10.3389/fphys.2019.01258. eCollection 2019.
Front Physiol. 2019.
PMID: 31632295
Free PMC article.
Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy.
Sapaly D, Dos Santos M, Delers P, Biondi O, Quérol G, Houdebine L, Khoobarry K, Girardet F, Burlet P, Armand AS, Chanoine C, Bureau JF, Charbonnier F, Lefebvre S.
Sapaly D, et al.
Sci Rep. 2018 Feb 1;8(1):2075. doi: 10.1038/s41598-018-20219-1.
Sci Rep. 2018.
PMID: 29391529
Free PMC article.
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Activating ATF6 in spinal muscular atrophy promotes SMN expression and motor neuron survival through the IRE1α-XBP1 pathway.
D'Amico D, Biondi O, Januel C, Bezier C, Sapaly D, Clerc Z, El Khoury M, Sundaram VK, Houdebine L, Josse T, Della Gaspera B, Martinat C, Massaad C, Weill L, Charbonnier F.
D'Amico D, et al. Among authors: sapaly d.
Neuropathol Appl Neurobiol. 2022 Aug;48(5):e12816. doi: 10.1111/nan.12816. Epub 2022 Mar 30.
Neuropathol Appl Neurobiol. 2022.
PMID: 35338505
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NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy.
El Khoury M, Biondi O, Bruneteau G, Sapaly D, Bendris S, Bezier C, Clerc Z, Akar EA, Weill L, Eid AA, Charbonnier F.
El Khoury M, et al. Among authors: sapaly d.
Front Cell Neurosci. 2023 Sep 14;17:1242828. doi: 10.3389/fncel.2023.1242828. eCollection 2023.
Front Cell Neurosci. 2023.
PMID: 37780204
Free PMC article.
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The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases.
Sapaly D, Delers P, Coridon J, Salman B, Letourneur F, Dumont F, Lefebvre S.
Sapaly D, et al.
Front Mol Biosci. 2020 Apr 17;7:55. doi: 10.3389/fmolb.2020.00055. eCollection 2020.
Front Mol Biosci. 2020.
PMID: 32363199
Free PMC article.
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A link between agrin signalling and Cav3.2 at the neuromuscular junction in spinal muscular atrophy.
Delers P, Sapaly D, Salman B, De Waard S, De Waard M, Lefebvre S.
Delers P, et al. Among authors: sapaly d.
Sci Rep. 2022 Nov 8;12(1):18960. doi: 10.1038/s41598-022-23703-x.
Sci Rep. 2022.
PMID: 36347955
Free PMC article.
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