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Base editing screens map mutations affecting interferon-γ signaling in cancer.
Cancer Cell. 2023 Feb 13;41(2):288-303.e6. doi: 10.1016/j.ccell.2022.12.009. Epub 2023 Jan 19.
Cancer Cell. 2023.
PMID: 36669486
Free PMC article.
Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy.
Picco G, Cattaneo CM, van Vliet EJ, Crisafulli G, Rospo G, Consonni S, Vieira SF, Rodríguez IS, Cancelliere C, Banerjee R, Schipper LJ, Oddo D, Dijkstra KK, Cinatl J, Michaelis M, Yang F, Di Nicolantonio F, Sartore-Bianchi A, Siena S, Arena S, Voest EE, Bardelli A, Garnett MJ; Cell Model Network UK Group.
Picco G, et al. Among authors: consonni s.
Cancer Discov. 2021 Aug;11(8):1923-1937. doi: 10.1158/2159-8290.CD-20-1508. Epub 2021 Apr 9.
Cancer Discov. 2021.
PMID: 33837064
Free article.
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DEP domains: structurally similar but functionally different.
Consonni SV, Maurice MM, Bos JL.
Consonni SV, et al.
Nat Rev Mol Cell Biol. 2014 May;15(5):357-62. doi: 10.1038/nrm3791. Epub 2014 Apr 16.
Nat Rev Mol Cell Biol. 2014.
PMID: 24739740
Review.
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The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.
Consonni SV, Brouwer PM, van Slobbe ES, Bos JL.
Consonni SV, et al.
PLoS One. 2014 May 23;9(5):e98253. doi: 10.1371/journal.pone.0098253. eCollection 2014.
PLoS One. 2014.
PMID: 24858808
Free PMC article.
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cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane.
Consonni SV, Gloerich M, Spanjaard E, Bos JL.
Consonni SV, et al.
Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3814-9. doi: 10.1073/pnas.1117599109. Epub 2012 Feb 16.
Proc Natl Acad Sci U S A. 2012.
PMID: 22343288
Free PMC article.
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