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CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity.
Long L, Wei J, Lim SA, Raynor JL, Shi H, Connelly JP, Wang H, Guy C, Xie B, Chapman NM, Fu G, Wang Y, Huang H, Su W, Saravia J, Risch I, Wang YD, Li Y, Niu M, Dhungana Y, Kc A, Zhou P, Vogel P, Yu J, Pruett-Miller SM, Peng J, Chi H. Long L, et al. Among authors: saravia j. Nature. 2021 Dec;600(7888):308-313. doi: 10.1038/s41586-021-04109-7. Epub 2021 Nov 18. Nature. 2021. PMID: 34795452 Free PMC article.
Helper T cell differentiation.
Saravia J, Chapman NM, Chi H. Saravia J, et al. Cell Mol Immunol. 2019 Jul;16(7):634-643. doi: 10.1038/s41423-019-0220-6. Epub 2019 Mar 12. Cell Mol Immunol. 2019. PMID: 30867582 Free PMC article. Review.
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy.
Wei J, Long L, Zheng W, Dhungana Y, Lim SA, Guy C, Wang Y, Wang YD, Qian C, Xu B, Kc A, Saravia J, Huang H, Yu J, Doench JG, Geiger TL, Chi H. Wei J, et al. Among authors: saravia j. Nature. 2019 Dec;576(7787):471-476. doi: 10.1038/s41586-019-1821-z. Epub 2019 Dec 11. Nature. 2019. PMID: 31827283 Free PMC article.
Homeostasis and transitional activation of regulatory T cells require c-Myc.
Saravia J, Zeng H, Dhungana Y, Bastardo Blanco D, Nguyen TM, Chapman NM, Wang Y, Kanneganti A, Liu S, Raynor JL, Vogel P, Neale G, Carmeliet P, Chi H. Saravia J, et al. Sci Adv. 2020 Jan 1;6(1):eaaw6443. doi: 10.1126/sciadv.aaw6443. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31911938 Free PMC article.
Signaling networks in immunometabolism.
Saravia J, Raynor JL, Chapman NM, Lim SA, Chi H. Saravia J, et al. Cell Res. 2020 Apr;30(4):328-342. doi: 10.1038/s41422-020-0301-1. Epub 2020 Mar 20. Cell Res. 2020. PMID: 32203134 Free PMC article. Review.
Lipid signalling enforces functional specialization of Treg cells in tumours.
Lim SA, Wei J, Nguyen TM, Shi H, Su W, Palacios G, Dhungana Y, Chapman NM, Long L, Saravia J, Vogel P, Chi H. Lim SA, et al. Among authors: saravia j. Nature. 2021 Mar;591(7849):306-311. doi: 10.1038/s41586-021-03235-6. Epub 2021 Feb 24. Nature. 2021. PMID: 33627871 Free PMC article.
mTORC2 forms iron-clad defense to guard memory.
Saravia J, Chi H. Saravia J, et al. Nat Immunol. 2022 Feb;23(2):155-156. doi: 10.1038/s41590-021-01100-2. Nat Immunol. 2022. PMID: 35058617 No abstract available.
72 results