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The Pan-Sirtuin Inhibitor MC2494 Regulates Mitochondrial Function in a Leukemia Cell Line.
Carafa V, Russo R, Della Torre L, Cuomo F, Dell'Aversana C, Sarno F, Sgueglia G, Di Donato M, Rotili D, Mai A, Nebbioso A, Cobellis G, Chambery A, Altucci L. Carafa V, et al. Among authors: sarno f. Front Oncol. 2020 May 21;10:820. doi: 10.3389/fonc.2020.00820. eCollection 2020. Front Oncol. 2020. PMID: 32528892 Free PMC article.
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies.
Brindisi M, Senger J, Cavella C, Grillo A, Chemi G, Gemma S, Cucinella DM, Lamponi S, Sarno F, Iside C, Nebbioso A, Novellino E, Shaik TB, Romier C, Herp D, Jung M, Butini S, Campiani G, Altucci L, Brogi S. Brindisi M, et al. Among authors: sarno f. Eur J Med Chem. 2018 Sep 5;157:127-138. doi: 10.1016/j.ejmech.2018.07.069. Epub 2018 Jul 31. Eur J Med Chem. 2018. PMID: 30092367
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease.
De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A. De Simone A, et al. Among authors: sarno f. ACS Med Chem Lett. 2019 Feb 4;10(4):469-474. doi: 10.1021/acsmedchemlett.8b00507. eCollection 2019 Apr 11. ACS Med Chem Lett. 2019. PMID: 30996781 Free PMC article.
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells.
Zwergel C, Schnekenburger M, Sarno F, Battistelli C, Manara MC, Stazi G, Mazzone R, Fioravanti R, Gros C, Ausseil F, Florean C, Nebbioso A, Strippoli R, Ushijima T, Scotlandi K, Tripodi M, Arimondo PB, Altucci L, Diederich M, Mai A, Valente S. Zwergel C, et al. Among authors: sarno f. Clin Epigenetics. 2019 May 6;11(1):68. doi: 10.1186/s13148-019-0663-8. Clin Epigenetics. 2019. PMID: 31060628 Free PMC article.
59 results