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Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.
Dominguez-Brauer C, Hao Z, Elia AJ, Fortin JM, Nechanitzky R, Brauer PM, Sheng Y, Mana MD, Chio IIC, Haight J, Pollett A, Cairns R, Tworzyanski L, Inoue S, Reardon C, Marques A, Silvester J, Cox MA, Wakeham A, Yilmaz OH, Sabatini DM, van Es JH, Clevers H, Sato T, Mak TW. Dominguez-Brauer C, et al. Among authors: sato t. Cell Stem Cell. 2016 Aug 4;19(2):205-216. doi: 10.1016/j.stem.2016.04.002. Epub 2016 May 12. Cell Stem Cell. 2016. PMID: 27184401 Free PMC article.
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro.
Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. Barker N, et al. Among authors: sato t. Cell Stem Cell. 2010 Jan 8;6(1):25-36. doi: 10.1016/j.stem.2009.11.013. Cell Stem Cell. 2010. PMID: 20085740 Free article.
Controlled gene expression in primary Lgr5 organoid cultures.
Koo BK, Stange DE, Sato T, Karthaus W, Farin HF, Huch M, van Es JH, Clevers H. Koo BK, et al. Among authors: sato t. Nat Methods. 2011 Dec 4;9(1):81-3. doi: 10.1038/nmeth.1802. Nat Methods. 2011. PMID: 22138822
On the biomechanics of stem cell niche formation in the gut--modelling growing organoids.
Buske P, Przybilla J, Loeffler M, Sachs N, Sato T, Clevers H, Galle J. Buske P, et al. Among authors: sato t. FEBS J. 2012 Sep;279(18):3475-87. doi: 10.1111/j.1742-4658.2012.08646.x. Epub 2012 Jun 18. FEBS J. 2012. PMID: 22632461 Free article.
In vitro culture of intestinal tissue has been attempted for decades. Only recently did Sato et al. [Sato, T., Vries, R. G., Snippert, H. J., van de Wetering, M., Barker, N., Stange, D. ...
In vitro culture of intestinal tissue has been attempted for decades. Only recently did Sato et al. [Sato, T., Vries, R …
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage.
van Es JH, Sato T, van de Wetering M, Lyubimova A, Yee Nee AN, Gregorieff A, Sasaki N, Zeinstra L, van den Born M, Korving J, Martens ACM, Barker N, van Oudenaarden A, Clevers H. van Es JH, et al. Among authors: sato t. Nat Cell Biol. 2012 Oct;14(10):1099-1104. doi: 10.1038/ncb2581. Epub 2012 Sep 23. Nat Cell Biol. 2012. PMID: 23000963 Free PMC article.
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