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Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1.
Sawada N, Kusudo T, Sakaki T, Hatakeyama S, Hanada M, Abe D, Kamao M, Okano T, Ohta M, Inouye K. Sawada N, et al. Biochemistry. 2004 Apr 20;43(15):4530-7. doi: 10.1021/bi030207f. Biochemistry. 2004. PMID: 15078099
Our previous study revealed that human CYP24A1 catalyzes a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways that used both 25(OH)D(3) and 1alpha,25(OH)(2)D(3) as substrates, while rat CYP24A1 showed extreme predominance of the C-24 over C-23 hydroxyla …
Our previous study revealed that human CYP24A1 catalyzes a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways tha …
Metabolism of vitamin D(3) by human CYP27A1.
Sawada N, Sakaki T, Ohta M, Inouye K. Sawada N, et al. Biochem Biophys Res Commun. 2000 Jul 14;273(3):977-84. doi: 10.1006/bbrc.2000.3050. Biochem Biophys Res Commun. 2000. PMID: 10891358
Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24.
Sakaki T, Sawada N, Komai K, Shiozawa S, Yamada S, Yamamoto K, Ohyama Y, Inouye K. Sakaki T, et al. Among authors: sawada n. Eur J Biochem. 2000 Oct;267(20):6158-65. doi: 10.1046/j.1432-1327.2000.01680.x. Eur J Biochem. 2000. PMID: 11012668 Free article.
Human CYP24 demonstrated a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways towards both 25(OH)D3 and 1alpha,25(OH)2D3, whereas rat CYP24 showed almost no C-23 hydroxylation pathway [Sakaki, T. Sawada, N. Nonaka, Y. Ohyama, Y. & Inou …
Human CYP24 demonstrated a remarkable metabolism consisting of both C-23 and C-24 hydroxylation pathways towards both 25(OH)D3 and 1alpha,25 …
1,318 results