Saxena AK - Search Results

1

Understanding histone deacetylases in the cancer development and treatment: an epigenetic perspective of cancer chemotherapy.

Ahmad M, Hamid A, Hussain A, Majeed R, Qurishi Y, Bhat JA, Najar RA, Qazi AK, Zargar MA, Singh SK, Saxena AK. Ahmad M, et al. Among authors: saxena ak. DNA Cell Biol. 2012 Oct;31 Suppl 1:S62-71. doi: 10.1089/dna.2011.1575. Epub 2012 Mar 30. DNA Cell Biol. 2012. PMID: 22462686 Review.

2

Recent development in targeting PI3K-Akt-mTOR signaling for anticancer therapeutic strategies.

Qazi AK, Hussain A, Hamid A, Qurishi Y, Majeed R, Ahmad M, Najar RA, Bhat JA, Singh SK, Zargar MA, Ali S, Saxena AK. Qazi AK, et al. Among authors: saxena ak. Anticancer Agents Med Chem. 2013 Dec;13(10):1552-64. doi: 10.2174/1871520613666131125123241. Anticancer Agents Med Chem. 2013. PMID: 23438828 Review.

3

NF-κB down-regulation and PARP cleavage by novel 3-α-butyryloxy-β-boswellic acid results in cancer cell specific apoptosis and in vivo tumor regression.

Qurishi Y, Hamid A, Sharma PR, Wani ZA, Mondhe DM, Singh SK, Zargar MA, Andotra SS, Shah BA, Taneja SC, Saxena AK. Qurishi Y, et al. Among authors: saxena ak. Anticancer Agents Med Chem. 2013 Jun;13(5):777-90. doi: 10.2174/1871520611313050012. Anticancer Agents Med Chem. 2013. PMID: 23157593

4

PI3K target based novel cyano derivative of betulinic acid induces its signalling inhibition by down-regulation of pGSK3β and cyclin D1 and potentially checks cancer cell proliferation.

Majeed R, Hussain A, Sangwan PL, Chinthakindi PK, Khan I, Sharma PR, Koul S, Saxena AK, Hamid A. Majeed R, et al. Among authors: saxena ak. Mol Carcinog. 2016 May;55(5):964-76. doi: 10.1002/mc.22339. Epub 2015 May 27. Mol Carcinog. 2016. PMID: 26013878

5

Interaction of natural products with cell survival and signaling pathways in the biochemical elucidation of drug targets in cancer.

Qurishi Y, Hamid A, Majeed R, Hussain A, Qazi AK, Ahmed M, Zargar MA, Singh SK, Saxena AK. Qurishi Y, et al. Among authors: saxena ak. Future Oncol. 2011 Aug;7(8):1007-21. doi: 10.2217/fon.11.69. Future Oncol. 2011. PMID: 21823895 Review.

6

PARP cleavage and perturbance in mitochondrial membrane potential by 3-α-propionyloxy-β-boswellic acid results in cancer cell death and tumor regression in murine models.

Qurishi Y, Hamid A, Sharma PR, Wani ZA, Mondhe DM, Singh SK, Zargar MA, Andotra SS, Shah BA, Taneja SC, Saxena AK. Qurishi Y, et al. Among authors: saxena ak. Future Oncol. 2012 Jul;8(7):867-81. doi: 10.2217/fon.12.68. Future Oncol. 2012. PMID: 22830406

7

Cell specific apoptosis by RLX is mediated by NFκB in human colon carcinoma HCT-116 cells.

Qazi AK, Hussain A, Aga MA, Ali S, Taneja SC, Sharma PR, Saxena AK, Mondhe DM, Hamid A. Qazi AK, et al. Among authors: saxena ak. BMC Cell Biol. 2014 Oct 10;15:36. doi: 10.1186/1471-2121-15-36. BMC Cell Biol. 2014. PMID: 25303828 Free PMC article.

8

Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.

Qazi AK, Hussain A, Khan S, Aga MA, Behl A, Ali S, Singh SK, Taneja SC, Shah BA, Saxena AK, Mondhe DM, Hamid A. Qazi AK, et al. Among authors: saxena ak. Cancer Lett. 2015 Apr 1;359(1):47-56. doi: 10.1016/j.canlet.2014.12.034. Epub 2014 Dec 29. Cancer Lett. 2015. PMID: 25554016

9

Bakuchiol derivatives as novel and potent cytotoxic agents: a report.

Majeed R, Reddy MV, Chinthakindi PK, Sangwan PL, Hamid A, Chashoo G, Saxena AK, Koul S. Majeed R, et al. Among authors: saxena ak. Eur J Med Chem. 2012 Mar;49:55-67. doi: 10.1016/j.ejmech.2011.12.018. Epub 2011 Dec 20. Eur J Med Chem. 2012. PMID: 22245048

10

Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability.

Singh B, Kumar A, Joshi P, Guru SK, Kumar S, Wani ZA, Mahajan G, Hussain A, Qazi AK, Kumar A, Bharate SS, Gupta BD, Sharma PR, Hamid A, Saxena AK, Mondhe DM, Bhushan S, Bharate SB, Vishwakarma RA. Singh B, et al. Among authors: saxena ak. Org Biomol Chem. 2015 May 28;13(20):5674-89. doi: 10.1039/c5ob00406c. Epub 2015 Apr 21. Org Biomol Chem. 2015. PMID: 25895604

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