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c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis.
Shimizu T, Ishikawa T, Sugihara E, Kuninaka S, Miyamoto T, Mabuchi Y, Matsuzaki Y, Tsunoda T, Miya F, Morioka H, Nakayama R, Kobayashi E, Toyama Y, Kawai A, Ichikawa H, Hasegawa T, Okada S, Ito T, Ikeda Y, Suda T, Saya H. Shimizu T, et al. Among authors: saya h. Oncogene. 2010 Oct 21;29(42):5687-99. doi: 10.1038/onc.2010.312. Epub 2010 Aug 2. Oncogene. 2010. PMID: 20676132
The cell cycle regulator Cdh1 controls the pool sizes of hematopoietic stem cells and mature lineage progenitors by protecting from genotoxic stress.
Ishizawa J, Kuninaka S, Sugihara E, Naoe H, Kobayashi Y, Chiyoda T, Ueki A, Araki K, Yamamura K, Matsuzaki Y, Nakajima H, Ikeda Y, Okamoto S, Saya H. Ishizawa J, et al. Among authors: saya h. Cancer Sci. 2011 May;102(5):967-74. doi: 10.1111/j.1349-7006.2011.01884.x. Epub 2011 Feb 23. Cancer Sci. 2011. PMID: 21255192 Free article.
CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth.
Ishimoto T, Nagano O, Yae T, Tamada M, Motohara T, Oshima H, Oshima M, Ikeda T, Asaba R, Yagi H, Masuko T, Shimizu T, Ishikawa T, Kai K, Takahashi E, Imamura Y, Baba Y, Ohmura M, Suematsu M, Baba H, Saya H. Ishimoto T, et al. Among authors: saya h. Cancer Cell. 2011 Mar 8;19(3):387-400. doi: 10.1016/j.ccr.2011.01.038. Cancer Cell. 2011. PMID: 21397861 Free article.
466 results