Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues.
Hart ME, Suchland KL, Miyakawa M, Bunzow JR, Grandy DK, Scanlan TS.
Hart ME, et al.
J Med Chem. 2006 Feb 9;49(3):1101-12. doi: 10.1021/jm0505718.
J Med Chem. 2006.
PMID: 16451074
We have previously shown that several thyronamines, decarboxylated and deiodinated metabolites of the thyroid hormone, potently activate an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale [Scanlan, T. S.; Such …
We have previously shown that several thyronamines, decarboxylated and deiodinated metabolites of the thyroid hormone, potently activate an …