Scapozza L - Search Results

1

Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets.

Jaquet V, Scapozza L, Clark RA, Krause KH, Lambeth JD. Jaquet V, et al. Among authors: scapozza l. Antioxid Redox Signal. 2009 Oct;11(10):2535-52. doi: 10.1089/ars.2009.2585. Antioxid Redox Signal. 2009. PMID: 19309261 Review.

2

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action.

Jaquet V, Marcoux J, Forest E, Leidal KG, McCormick S, Westermaier Y, Perozzo R, Plastre O, Fioraso-Cartier L, Diebold B, Scapozza L, Nauseef WM, Fieschi F, Krause KH, Bedard K. Jaquet V, et al. Among authors: scapozza l. Br J Pharmacol. 2011 Sep;164(2b):507-20. doi: 10.1111/j.1476-5381.2011.01439.x. Br J Pharmacol. 2011. PMID: 21501142 Free PMC article.

3

Diapocynin, a dimer of the NADPH oxidase inhibitor apocynin, reduces ROS production and prevents force loss in eccentrically contracting dystrophic muscle.

Ismail HM, Scapozza L, Ruegg UT, Dorchies OM. Ismail HM, et al. Among authors: scapozza l. PLoS One. 2014 Oct 17;9(10):e110708. doi: 10.1371/journal.pone.0110708. eCollection 2014. PLoS One. 2014. PMID: 25329652 Free PMC article.

4

A subset of N-substituted phenothiazines inhibits NADPH oxidases.

Seredenina T, Chiriano G, Filippova A, Nayernia Z, Mahiout Z, Fioraso-Cartier L, Plastre O, Scapozza L, Krause KH, Jaquet V. Seredenina T, et al. Among authors: scapozza l. Free Radic Biol Med. 2015 Sep;86:239-49. doi: 10.1016/j.freeradbiomed.2015.05.023. Epub 2015 May 23. Free Radic Biol Med. 2015. PMID: 26013584

5

Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation.

Preynat-Seauve O, Nguyen EB, Westermaier Y, Héritier M, Tardy S, Cambet Y, Feyeux M, Caillon A, Scapozza L, Krause KH. Preynat-Seauve O, et al. Among authors: scapozza l. Front Pharmacol. 2021 Aug 4;12:664608. doi: 10.3389/fphar.2021.664608. eCollection 2021. Front Pharmacol. 2021. PMID: 34421588 Free PMC article.

6

Inhibition of iPLA2 β and of stretch-activated channels by doxorubicin alters dystrophic muscle function.

Ismail HM, Dorchies OM, Perozzo R, Strosova MK, Scapozza L, Ruegg UT. Ismail HM, et al. Among authors: scapozza l. Br J Pharmacol. 2013 Aug;169(7):1537-50. doi: 10.1111/bph.12188. Br J Pharmacol. 2013. PMID: 23849042 Free PMC article.

7

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation.

Conus S, Perozzo R, Reinheckel T, Peters C, Scapozza L, Yousefi S, Simon HU. Conus S, et al. Among authors: scapozza l. J Exp Med. 2008 Mar 17;205(3):685-98. doi: 10.1084/jem.20072152. Epub 2008 Feb 25. J Exp Med. 2008. PMID: 18299403 Free PMC article.

8

Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics.

Kuettel S, Mosimann M, Mäser P, Kaiser M, Brun R, Scapozza L, Perozzo R. Kuettel S, et al. Among authors: scapozza l. PLoS Negl Trop Dis. 2009 Aug 25;3(8):e506. doi: 10.1371/journal.pntd.0000506. PLoS Negl Trop Dis. 2009. PMID: 19707572 Free PMC article.

9

Single-molecule pulling simulations can discern active from inactive enzyme inhibitors.

Colizzi F, Perozzo R, Scapozza L, Recanatini M, Cavalli A. Colizzi F, et al. Among authors: scapozza l. J Am Chem Soc. 2010 Jun 2;132(21):7361-71. doi: 10.1021/ja100259r. J Am Chem Soc. 2010. PMID: 20462212

10

RET kinase inhibitors: a review of recent patents (2012-2015).

Mologni L, Gambacorti-Passerini C, Goekjian P, Scapozza L. Mologni L, et al. Among authors: scapozza l. Expert Opin Ther Pat. 2017 Jan;27(1):91-99. doi: 10.1080/13543776.2017.1238073. Epub 2016 Sep 26. Expert Opin Ther Pat. 2017. PMID: 27646564 Review.

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