Schärer OD - Search Results

1

Crosslinking of the NER damage recognition proteins XPC-HR23B, XPA and RPA to photoreactive probes that mimic DNA damages.

Maltseva EA, Rechkunova NI, Gillet LC, Petruseva IO, Schärer OD, Lavrik OI. Maltseva EA, et al. Among authors: scharer od. Biochim Biophys Acta. 2007 May;1770(5):781-9. doi: 10.1016/j.bbagen.2007.01.007. Epub 2007 Jan 25. Biochim Biophys Acta. 2007. PMID: 17320292

2

Preparation of C8-amine and acetylamine adducts of 2'-deoxyguanosine suitably protected for DNA synthesis.

Gillet LC, Schärer OD. Gillet LC, et al. Among authors: scharer od. Org Lett. 2002 Nov 28;4(24):4205-8. doi: 10.1021/ol026474f. Org Lett. 2002. PMID: 12443059

3

Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis.

Gillet LC, Alzeer J, Schärer OD. Gillet LC, et al. Among authors: scharer od. Nucleic Acids Res. 2005 Apr 6;33(6):1961-9. doi: 10.1093/nar/gki335. Print 2005. Nucleic Acids Res. 2005. PMID: 15814813 Free PMC article.

4

Molecular mechanisms of mammalian global genome nucleotide excision repair.

Gillet LC, Schärer OD. Gillet LC, et al. Among authors: scharer od. Chem Rev. 2006 Feb;106(2):253-76. doi: 10.1021/cr040483f. Chem Rev. 2006. PMID: 16464005 Review. No abstract available.

5

Crosslinking of nucleotide excision repair proteins with DNA containing photoreactive damages.

Maltseva EA, Rechkunova NI, Petruseva IO, Vermeulen W, Schärer OD, Lavrik OI. Maltseva EA, et al. Among authors: scharer od. Bioorg Chem. 2008 Apr;36(2):77-84. doi: 10.1016/j.bioorg.2007.11.004. Epub 2008 Jan 11. Bioorg Chem. 2008. PMID: 18191172

6

Interaction of nucleotide excision repair factors XPC-HR23B, XPA, and RPA with damaged DNA.

Krasikova YS, Rechkunova NI, Maltseva EA, Petruseva IO, Silnikov VN, Zatsepin TS, Oretskaya TS, Schärer OD, Lavrik OI. Krasikova YS, et al. Among authors: scharer od. Biochemistry (Mosc). 2008 Aug;73(8):886-96. doi: 10.1134/s0006297908080063. Biochemistry (Mosc). 2008. PMID: 18774935

7

A key interaction with RPA orients XPA in NER complexes.

Topolska-Woś AM, Sugitani N, Cordoba JJ, Le Meur KV, Le Meur RA, Kim HS, Yeo JE, Rosenberg D, Hammel M, Schärer OD, Chazin WJ. Topolska-Woś AM, et al. Among authors: scharer od. Nucleic Acids Res. 2020 Feb 28;48(4):2173-2188. doi: 10.1093/nar/gkz1231. Nucleic Acids Res. 2020. PMID: 31925419 Free PMC article.

8

Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair.

Kim M, Kim HS, D'Souza A, Gallagher K, Jeong E, Topolska-Wós A, Ogorodnik Le Meur K, Tsai CL, Tsai MS, Kee M, Tainer JA, Yeo JE, Chazin WJ, Schärer OD. Kim M, et al. Among authors: scharer od. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2207408119. doi: 10.1073/pnas.2207408119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969784 Free PMC article.

9

A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair.

van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, Schärer OD, Luijsterburg MS. van den Heuvel D, et al. Among authors: scharer od. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2208860120. doi: 10.1073/pnas.2208860120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893274 Free PMC article.

10

Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA.

Tsodikov OV, Ivanov D, Orelli B, Staresincic L, Shoshani I, Oberman R, Schärer OD, Wagner G, Ellenberger T. Tsodikov OV, et al. Among authors: scharer od. EMBO J. 2007 Nov 14;26(22):4768-76. doi: 10.1038/sj.emboj.7601894. Epub 2007 Oct 18. EMBO J. 2007. PMID: 17948053 Free PMC article.

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