Schadt EE - Search Results

1

Variations in DNA elucidate molecular networks that cause disease.

Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE. Chen Y, et al. Among authors: schadt ee. Nature. 2008 Mar 27;452(7186):429-35. doi: 10.1038/nature06757. Epub 2008 Mar 16. Nature. 2008. PMID: 18344982 Free PMC article.

2

Genetics of gene expression surveyed in maize, mouse and man.

Schadt EE, Monks SA, Drake TA, Lusis AJ, Che N, Colinayo V, Ruff TG, Milligan SB, Lamb JR, Cavet G, Linsley PS, Mao M, Stoughton RB, Friend SH. Schadt EE, et al. Nature. 2003 Mar 20;422(6929):297-302. doi: 10.1038/nature01434. Nature. 2003. PMID: 12646919

3

An integrative genomics approach to infer causal associations between gene expression and disease.

Schadt EE, Lamb J, Yang X, Zhu J, Edwards S, Guhathakurta D, Sieberts SK, Monks S, Reitman M, Zhang C, Lum PY, Leonardson A, Thieringer R, Metzger JM, Yang L, Castle J, Zhu H, Kash SF, Drake TA, Sachs A, Lusis AJ. Schadt EE, et al. Nat Genet. 2005 Jul;37(7):710-7. doi: 10.1038/ng1589. Epub 2005 Jun 19. Nat Genet. 2005. PMID: 15965475 Free PMC article.

4

Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes.

Schadt EE, Lum PY. Schadt EE, et al. J Lipid Res. 2006 Dec;47(12):2601-13. doi: 10.1194/jlr.R600026-JLR200. Epub 2006 Oct 1. J Lipid Res. 2006. PMID: 17012750 Free article. Review.

5

Moving toward a system genetics view of disease.

Sieberts SK, Schadt EE. Sieberts SK, et al. Among authors: schadt ee. Mamm Genome. 2007 Jul;18(6-7):389-401. doi: 10.1007/s00335-007-9040-6. Epub 2007 Jul 26. Mamm Genome. 2007. PMID: 17653589 Free PMC article. Review.

6

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks.

Zhu J, Zhang B, Smith EN, Drees B, Brem RB, Kruglyak L, Bumgarner RE, Schadt EE. Zhu J, et al. Among authors: schadt ee. Nat Genet. 2008 Jul;40(7):854-61. doi: 10.1038/ng.167. Epub 2008 Jun 15. Nat Genet. 2008. PMID: 18552845 Free PMC article.

7

Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.

Lum PY, Chen Y, Zhu J, Lamb J, Melmed S, Wang S, Drake TA, Lusis AJ, Schadt EE. Lum PY, et al. Among authors: schadt ee. J Neurochem. 2006 Apr;97 Suppl 1:50-62. doi: 10.1111/j.1471-4159.2006.03661.x. J Neurochem. 2006. PMID: 16635250 Free article.

8

Cis-acting expression quantitative trait loci in mice.

Doss S, Schadt EE, Drake TA, Lusis AJ. Doss S, et al. Among authors: schadt ee. Genome Res. 2005 May;15(5):681-91. doi: 10.1101/gr.3216905. Epub 2005 Apr 18. Genome Res. 2005. PMID: 15837804 Free PMC article.

9

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels.

Cervino AC, Li G, Edwards S, Zhu J, Laurie C, Tokiwa G, Lum PY, Wang S, Castellani LW, Lusis AJ, Carlson S, Sachs AB, Schadt EE. Cervino AC, et al. Among authors: schadt ee. Genomics. 2005 Nov;86(5):505-17. doi: 10.1016/j.ygeno.2005.07.010. Epub 2005 Aug 29. Genomics. 2005. PMID: 16126366

10

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits.

Mehrabian M, Allayee H, Stockton J, Lum PY, Drake TA, Castellani LW, Suh M, Armour C, Edwards S, Lamb J, Lusis AJ, Schadt EE. Mehrabian M, et al. Among authors: schadt ee. Nat Genet. 2005 Nov;37(11):1224-33. doi: 10.1038/ng1619. Epub 2005 Oct 2. Nat Genet. 2005. PMID: 16200066

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