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PI3K/mTOR inhibition induces tumour microenvironment remodelling and sensitises pS6high uterine leiomyosarcoma to PD-1 blockade.
De Wispelaere W, Annibali D, Tuyaerts S, Messiaen J, Antoranz A, Shankar G, Dubroja N, Herreros-Pomares A, Baiden-Amissah REM, Orban MP, Delfini M, Berardi E, Van Brussel T, Schepers R, Philips G, Boeckx B, Baietti MF, Congedo L, HoWangYin KY, Bayon E, Van Rompuy AS, Leucci E, Tabruyn SP, Bosisio F, Mazzone M, Lambrechts D, Amant F. De Wispelaere W, et al. Among authors: schepers r. Clin Transl Med. 2024 May;14(5):e1655. doi: 10.1002/ctm2.1655. Clin Transl Med. 2024. PMID: 38711203
Single-cell Atlas of Penile Cancer Reveals TP53 Mutations as a Driver of an Aggressive Phenotype, Irrespective of Human Papillomavirus Status, and Provides Clues for Treatment Personalization.
Elst L, Philips G, Vandermaesen K, Bassez A, Lodi F, Vreeburg MTA, Brouwer OR, Schepers R, Van Brussel T, Mohanty SK, Parwani AV, Spans L, Vanden Bempt I, Jacomen G, Baldewijns M, Lambrechts D, Albersen M. Elst L, et al. Among authors: schepers r. Eur Urol. 2024 Apr 25:S0302-2838(24)02266-8. doi: 10.1016/j.eururo.2024.03.038. Online ahead of print. Eur Urol. 2024. PMID: 38670879
Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program.
Geukens T, De Schepper M, Van Den Bogaert W, Van Baelen K, Maetens M, Pabba A, Mahdami A, Leduc S, Isnaldi E, Nguyen HL, Bachir I, Hajipirloo M, Zels G, Van Cauwenberge J, Borremans K, Vandecaveye V, Weynand B, Vermeulen P, Leucci E, Baietti MF, Sflomos G, Battista L, Brisken C, Derksen PWB, Koorman T, Visser D, Scheele CLGJ, Thommen DS, Hatse S, Fendt SM, Vanderheyden E, Van Brussel T, Schepers R, Boeckx B, Lambrechts D, Marano G, Biganzoli E, Smeets A, Nevelsteen I, Punie K, Neven P, Wildiers H, Richard F, Floris G, Desmedt C. Geukens T, et al. Among authors: schepers r. NPJ Breast Cancer. 2024 Apr 24;10(1):31. doi: 10.1038/s41523-024-00637-3. NPJ Breast Cancer. 2024. PMID: 38658604 Free PMC article.
Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases.
Leduc S, Nguyen HL, Richard F, Zels G, Mahdami A, De Schepper M, Maetens M, Pabba A, Jaekers J, Latacz E, Bohlok A, Vanderheyden E, Van Brussel T, Boeckx B, Schepers R, Lambrechts D, Dirix L, Larsimont D, Vankerckhove S, Lucidi V, Topal B, Bachir I, Donckier V, Floris G, Vermeulen P, Desmedt C. Leduc S, et al. Among authors: schepers r. Clin Exp Metastasis. 2024 Mar 29. doi: 10.1007/s10585-024-10279-1. Online ahead of print. Clin Exp Metastasis. 2024. PMID: 38548918
134 results