Schmidhammer H - Search Results

1

Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice.

Spetea M, Eans SO, Ganno ML, Lantero A, Mairegger M, Toll L, Schmidhammer H, McLaughlin JP. Spetea M, et al. Among authors: schmidhammer h. Br J Pharmacol. 2017 Aug;174(15):2444-2456. doi: 10.1111/bph.13854. Epub 2017 Jun 27. Br J Pharmacol. 2017. PMID: 28494108 Free PMC article.

2

Binding, pharmacological and immunological profiles of the delta-selective opioid receptor antagonist HS 378.

Spetea M, Harris HE, Berzetei-Gurske IP, Klareskog L, Schmidhammer H. Spetea M, et al. Among authors: schmidhammer h. Life Sci. 2001 Aug 31;69(15):1775-82. doi: 10.1016/s0024-3205(01)01271-1. Life Sci. 2001. PMID: 11665839

3

Synthesis and biological evaluation of 14-alkoxymorphinans. 17. Highly delta opioid receptor selective 14-alkoxy-substituted indolo- and benzofuromorphinans.

Schütz J, Dersch CM, Horel R, Spetea M, Koch M, Meditz R, Greiner E, Rothman RB, Schmidhammer H. Schütz J, et al. Among authors: schmidhammer h. J Med Chem. 2002 Nov 21;45(24):5378-83. doi: 10.1021/jm020940p. J Med Chem. 2002. PMID: 12431065

4

Synthesis and biological evaluation of 14-alkoxymorphinans. 18. N-substituted 14-phenylpropyloxymorphinan-6-ones with unanticipated agonist properties: extending the scope of common structure-activity relationships.

Greiner E, Spetea M, Krassnig R, Schüllner F, Aceto M, Harris LS, Traynor JR, Woods JH, Coop A, Schmidhammer H. Greiner E, et al. Among authors: schmidhammer h. J Med Chem. 2003 Apr 24;46(9):1758-63. doi: 10.1021/jm021118o. J Med Chem. 2003. PMID: 12699394

5

Binding characteristics of [3H]14-methoxymetopon, a high affinity mu-opioid receptor agonist.

Spetea M, Tóth F, Schütz J, Otvös F, Tóth G, Benyhe S, Borsodi A, Schmidhammer H. Spetea M, et al. Among authors: schmidhammer h. Eur J Neurosci. 2003 Jul;18(2):290-5. doi: 10.1046/j.1460-9568.2003.02744.x. Eur J Neurosci. 2003. PMID: 12887410

6

Synthesis and biological evaluation of 14-alkoxymorphinans. 20. 14-phenylpropoxymetopon: an extremely powerful analgesic.

Schütz J, Spetea M, Koch M, Aceto MD, Harris LS, Coop A, Schmidhammer H. Schütz J, et al. Among authors: schmidhammer h. J Med Chem. 2003 Sep 11;46(19):4182-7. doi: 10.1021/jm030878b. J Med Chem. 2003. PMID: 12954070

7

In vitro opioid activity profiles of 6-amino acid substituted derivatives of 14-O-methyloxymorphone.

Spetea M, Friedmann T, Riba P, Schütz J, Wunder G, Langer T, Schmidhammer H, Fürst S. Spetea M, et al. Among authors: schmidhammer h. Eur J Pharmacol. 2004 Jan 12;483(2-3):301-8. doi: 10.1016/j.ejphar.2003.10.049. Eur J Pharmacol. 2004. PMID: 14729121

8

Synthesis and biological evaluation of 14-alkoxymorphinans. 21. Novel 4-alkoxy and 14-phenylpropoxy derivatives of the mu opioid receptor antagonist cyprodime.

Spetea M, Schüllner F, Moisa RC, Berzetei-Gurske IP, Schraml B, Dörfler C, Aceto MD, Harris LS, Coop A, Schmidhammer H. Spetea M, et al. Among authors: schmidhammer h. J Med Chem. 2004 Jun 3;47(12):3242-7. doi: 10.1021/jm031126k. J Med Chem. 2004. PMID: 15163203

9

Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat.

Fürst S, Riba P, Friedmann T, Tímar J, Al-Khrasani M, Obara I, Makuch W, Spetea M, Schütz J, Przewlocki R, Przewlocka B, Schmidhammer H. Fürst S, et al. Among authors: schmidhammer h. J Pharmacol Exp Ther. 2005 Feb;312(2):609-18. doi: 10.1124/jpet.104.075176. Epub 2004 Sep 21. J Pharmacol Exp Ther. 2005. PMID: 15383636

10

Synthesis and biological evaluation of 14-alkoxymorphinans. 22.(1) Influence of the 14-alkoxy group and the substitution in position 5 in 14-alkoxymorphinan-6-ones on in vitro and in vivo activities.

Lattanzi R, Spetea M, Schüllner F, Rief SB, Krassnig R, Negri L, Schmidhammer H. Lattanzi R, et al. Among authors: schmidhammer h. J Med Chem. 2005 May 5;48(9):3372-8. doi: 10.1021/jm040894o. J Med Chem. 2005. PMID: 15857143

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