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Two naturally occurring mouse alpha-1,2-mannosidase IB cDNA clones differ in three point mutations. Mutation of Phe592 to Ser592 is sufficient to abolish enzyme activity.
Schneikert J, Herscovics A. Schneikert J, et al. J Biol Chem. 1995 Jul 28;270(30):17736-40. doi: 10.1074/jbc.270.30.17736. J Biol Chem. 1995. PMID: 7629073 Free article.
In mammalian cells, alpha-1,2-mannosidases play an essential role in the early steps of N-linked oligosaccharide maturation. We previously reported (Herscovics, A., Schneikert, J., Athanassiadis, A., and Moremen, K. W. (1994) J. Biol. ...
In mammalian cells, alpha-1,2-mannosidases play an essential role in the early steps of N-linked oligosaccharide maturation. We previously r …
35 results