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VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response.
Thisted T, Smith FD, Mukherjee A, Kleschenko Y, Feng F, Jiang ZG, Eitas T, Malhotra K, Biesova Z, Onumajuru A, Finley F, Cifuentes A, Zhang G, Martin GH, Takeuchi Y, Thiam K, Schreiber RD, van der Horst EH. Thisted T, et al. Among authors: schreiber rd. Nat Commun. 2024 Apr 4;15(1):2917. doi: 10.1038/s41467-024-47256-x. Nat Commun. 2024. PMID: 38575562 Free PMC article.
IL-2 targeted to CD8+ T cells promotes robust effector T cell responses and potent antitumor immunity.
Moynihan KD, Kumar MP, Sultan H, Pappas DC, Park T, Chin SM, Bessette P, Lan RY, Nguyen HC, Mathewson ND, Ni I, Chen W, Lee Y, Liao-Chan S, Chen J, Schumacher TNM, Schreiber RD, Yeung YA, Djuretic IM. Moynihan KD, et al. Among authors: schreiber rd. Cancer Discov. 2024 Apr 2. doi: 10.1158/2159-8290.CD-23-1266. Online ahead of print. Cancer Discov. 2024. PMID: 38563906
CD5 expression by dendritic cells directs T cell immunity and sustains immunotherapy responses.
He M, Roussak K, Ma F, Borcherding N, Garin V, White M, Schutt C, Jensen TI, Zhao Y, Iberg CA, Shah K, Bhatia H, Korenfeld D, Dinkel S, Gray J, Ulezko Antonova A, Ferris S, Donermeyer D, Lindestam Arlehamn C, Gubin MM, Luo J, Gorvel L, Pellegrini M, Sette A, Tung T, Bak R, Modlin RL, Fields RC, Schreiber RD, Allen PM, Klechevsky E. He M, et al. Among authors: schreiber rd. Science. 2023 Feb 17;379(6633):eabg2752. doi: 10.1126/science.abg2752. Epub 2023 Feb 17. Science. 2023. PMID: 36795805 Free PMC article.
Emil R. Unanue (1934-2022).
Yokoyama WM, Murphy KM, Schreiber RD, Colonna M. Yokoyama WM, et al. Among authors: schreiber rd. Immunity. 2023 Feb 14;56(2):225-226. doi: 10.1016/j.immuni.2023.01.006. Immunity. 2023. PMID: 36792565 No abstract available.
311 results