Schweighoffer E - Search Results

1

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.

Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J. Gross O, et al. Among authors: schweighoffer e. Nature. 2009 May 21;459(7245):433-6. doi: 10.1038/nature07965. Epub 2009 Apr 1. Nature. 2009. PMID: 19339971

2

Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases.

Colucci F, Schweighoffer E, Tomasello E, Turner M, Ortaldo JR, Vivier E, Tybulewicz VL, Di Santo JP. Colucci F, et al. Among authors: schweighoffer e. Nat Immunol. 2002 Mar;3(3):288-94. doi: 10.1038/ni764. Epub 2002 Feb 11. Nat Immunol. 2002. PMID: 11836527

3

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.

LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, Reis e Sousa C. LeibundGut-Landmann S, et al. Among authors: schweighoffer e. Nat Immunol. 2007 Jun;8(6):630-8. doi: 10.1038/ni1460. Epub 2007 Apr 22. Nat Immunol. 2007. PMID: 17450144

4

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection.

Robinson MJ, Osorio F, Rosas M, Freitas RP, Schweighoffer E, Gross O, Verbeek JS, Ruland J, Tybulewicz V, Brown GD, Moita LF, Taylor PR, Reis e Sousa C. Robinson MJ, et al. Among authors: schweighoffer e. J Exp Med. 2009 Aug 31;206(9):2037-51. doi: 10.1084/jem.20082818. Epub 2009 Aug 24. J Exp Med. 2009. PMID: 19703985 Free PMC article.

5

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.

Hara H, Tsuchiya K, Kawamura I, Fang R, Hernandez-Cuellar E, Shen Y, Mizuguchi J, Schweighoffer E, Tybulewicz V, Mitsuyama M. Hara H, et al. Among authors: schweighoffer e. Nat Immunol. 2013 Dec;14(12):1247-55. doi: 10.1038/ni.2749. Epub 2013 Nov 3. Nat Immunol. 2013. PMID: 24185614 Free PMC article.

6

Signalling for B cell survival.

Schweighoffer E, Tybulewicz VL. Schweighoffer E, et al. Curr Opin Cell Biol. 2018 Apr;51:8-14. doi: 10.1016/j.ceb.2017.10.002. Epub 2017 Nov 14. Curr Opin Cell Biol. 2018. PMID: 29149682 Free article. Review.

7

NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases.

Zompi S, Hamerman JA, Ogasawara K, Schweighoffer E, Tybulewicz VL, Di Santo JP, Lanier LL, Colucci F. Zompi S, et al. Among authors: schweighoffer e. Nat Immunol. 2003 Jun;4(6):565-72. doi: 10.1038/ni930. Epub 2003 May 11. Nat Immunol. 2003. PMID: 12740576 Free article.

8

Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.

Ackermann JA, Nys J, Schweighoffer E, McCleary S, Smithers N, Tybulewicz VL. Ackermann JA, et al. Among authors: schweighoffer e. J Immunol. 2015 May 15;194(10):4650-6. doi: 10.4049/jimmunol.1500461. Epub 2015 Apr 10. J Immunol. 2015. PMID: 25862820 Free PMC article.

9

Tyrosine kinase SYK: essential functions for immunoreceptor signalling.

Turner M, Schweighoffer E, Colucci F, Di Santo JP, Tybulewicz VL. Turner M, et al. Among authors: schweighoffer e. Immunol Today. 2000 Mar;21(3):148-54. doi: 10.1016/s0167-5699(99)01574-1. Immunol Today. 2000. PMID: 10689303 Review.

10

Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan.

Slack EC, Robinson MJ, Hernanz-Falcón P, Brown GD, Williams DL, Schweighoffer E, Tybulewicz VL, Reis e Sousa C. Slack EC, et al. Among authors: schweighoffer e. Eur J Immunol. 2007 Jun;37(6):1600-12. doi: 10.1002/eji.200636830. Eur J Immunol. 2007. PMID: 17458858 Free article.

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