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Filgrastim biosimilar (EP2006): A review of 15 years' post-approval evidence.
Gascón P, Harbeck N, Rapoport BL, Anderson R, Brueckmann I, Howe S, Aapro M. Gascón P, et al. Among authors: howe s. Crit Rev Oncol Hematol. 2024 Apr;196:104306. doi: 10.1016/j.critrevonc.2024.104306. Epub 2024 Feb 23. Crit Rev Oncol Hematol. 2024. PMID: 38401695 Free article. Review.
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.
Such L, Zhao F, Liu D, Thier B, Le-Trilling VTK, Sucker A, Coch C, Pieper N, Howe S, Bhat H, Kalkavan H, Ritter C, Brinkhaus R, Ugurel S, Köster J, Seifert U, Dittmer U, Schuler M, Lang KS, Kufer TA, Hartmann G, Becker JC, Horn S, Ferrone S, Liu D, Van Allen EM, Schadendorf D, Griewank K, Trilling M, Paschen A. Such L, et al. Among authors: howe s. J Clin Invest. 2020 Aug 3;130(8):4266-4281. doi: 10.1172/JCI131572. J Clin Invest. 2020. PMID: 32427578 Free PMC article.
Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions.
Sucker A, Zhao F, Pieper N, Heeke C, Maltaner R, Stadtler N, Real B, Bielefeld N, Howe S, Weide B, Gutzmer R, Utikal J, Loquai C, Gogas H, Klein-Hitpass L, Zeschnigk M, Westendorf AM, Trilling M, Horn S, Schilling B, Schadendorf D, Griewank KG, Paschen A. Sucker A, et al. Among authors: howe s. Nat Commun. 2017 May 31;8:15440. doi: 10.1038/ncomms15440. Nat Commun. 2017. PMID: 28561041 Free PMC article.
Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11.
Nouri K, Moll JM, Milroy LG, Hain A, Dvorsky R, Amin E, Lenders M, Nagel-Steger L, Howe S, Smits SH, Hengel H, Schmitt L, Münk C, Brunsveld L, Ahmadian MR. Nouri K, et al. Among authors: howe s. PLoS One. 2015 Dec 1;10(12):e0143634. doi: 10.1371/journal.pone.0143634. eCollection 2015. PLoS One. 2015. PMID: 26624888 Free PMC article.
A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx.
Landsberg CD, Megger DA, Hotter D, Rückborn MU, Eilbrecht M, Rashidi-Alavijeh J, Howe S, Heinrichs S, Sauter D, Sitek B, Le-Trilling VTK, Trilling M. Landsberg CD, et al. Among authors: howe s. Front Immunol. 2018 Dec 19;9:2978. doi: 10.3389/fimmu.2018.02978. eCollection 2018. Front Immunol. 2018. PMID: 30619335 Free PMC article.