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Page 1
Expression system for structural and functional studies of human glycosylation enzymes.
Moremen KW, Ramiah A, Stuart M, Steel J, Meng L, Forouhar F, Moniz HA, Gahlay G, Gao Z, Chapla D, Wang S, Yang JY, Prabhakar PK, Johnson R, Rosa MD, Geisler C, Nairn AV, Seetharaman J, Wu SC, Tong L, Gilbert HJ, LaBaer J, Jarvis DL. Moremen KW, et al. Among authors: seetharaman j. Nat Chem Biol. 2018 Feb;14(2):156-162. doi: 10.1038/nchembio.2539. Epub 2017 Dec 18. Nat Chem Biol. 2018. PMID: 29251719 Free PMC article.
Enzymatic basis for N-glycan sialylation: structure of rat α2,6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation.
Meng L, Forouhar F, Thieker D, Gao Z, Ramiah A, Moniz H, Xiang Y, Seetharaman J, Milaninia S, Su M, Bridger R, Veillon L, Azadi P, Kornhaber G, Wells L, Montelione GT, Woods RJ, Tong L, Moremen KW. Meng L, et al. Among authors: seetharaman j. J Biol Chem. 2013 Nov 29;288(48):34680-98. doi: 10.1074/jbc.M113.519041. Epub 2013 Oct 23. J Biol Chem. 2013. PMID: 24155237 Free PMC article.
Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases.
Forouhar F, Arragain S, Atta M, Gambarelli S, Mouesca JM, Hussain M, Xiao R, Kieffer-Jaquinod S, Seetharaman J, Acton TB, Montelione GT, Mulliez E, Hunt JF, Fontecave M. Forouhar F, et al. Among authors: seetharaman j. Nat Chem Biol. 2013 May;9(5):333-8. doi: 10.1038/nchembio.1229. Epub 2013 Mar 31. Nat Chem Biol. 2013. PMID: 23542644 Free PMC article.
Structures of bacterial biosynthetic arginine decarboxylases.
Forouhar F, Lew S, Seetharaman J, Xiao R, Acton TB, Montelione GT, Tong L. Forouhar F, et al. Among authors: seetharaman j. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1;66(Pt 12):1562-6. doi: 10.1107/S1744309110040649. Epub 2010 Nov 16. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 21139196 Free PMC article.
Functional insights from structural genomics.
Forouhar F, Kuzin A, Seetharaman J, Lee I, Zhou W, Abashidze M, Chen Y, Yong W, Janjua H, Fang Y, Wang D, Cunningham K, Xiao R, Acton TB, Pichersky E, Klessig DF, Porter CW, Montelione GT, Tong L. Forouhar F, et al. Among authors: seetharaman j. J Struct Funct Genomics. 2007 Sep;8(2-3):37-44. doi: 10.1007/s10969-007-9018-3. Epub 2007 Jun 23. J Struct Funct Genomics. 2007. PMID: 17588214
A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding.
Forouhar F, Saadat N, Hussain M, Seetharaman J, Lee I, Janjua H, Xiao R, Shastry R, Acton TB, Montelione GT, Tong L. Forouhar F, et al. Among authors: seetharaman j. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Nov 1;67(Pt 11):1323-7. doi: 10.1107/S1744309111031447. Epub 2011 Oct 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22102225 Free PMC article.
NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway.
Liu G, Forouhar F, Eletsky A, Atreya HS, Aramini JM, Xiao R, Huang YJ, Abashidze M, Seetharaman J, Liu J, Rost B, Acton T, Montelione GT, Hunt JF, Szyperski T. Liu G, et al. Among authors: seetharaman j. J Struct Funct Genomics. 2009 Apr;10(2):127-36. doi: 10.1007/s10969-008-9054-7. Epub 2008 Dec 20. J Struct Funct Genomics. 2009. PMID: 19101823 Free PMC article.
A community resource of experimental data for NMR / X-ray crystal structure pairs.
Everett JK, Tejero R, Murthy SB, Acton TB, Aramini JM, Baran MC, Benach J, Cort JR, Eletsky A, Forouhar F, Guan R, Kuzin AP, Lee HW, Liu G, Mani R, Mao B, Mills JL, Montelione AF, Pederson K, Powers R, Ramelot T, Rossi P, Seetharaman J, Snyder D, Swapna GV, Vorobiev SM, Wu Y, Xiao R, Yang Y, Arrowsmith CH, Hunt JF, Kennedy MA, Prestegard JH, Szyperski T, Tong L, Montelione GT. Everett JK, et al. Among authors: seetharaman j. Protein Sci. 2016 Jan;25(1):30-45. doi: 10.1002/pro.2774. Epub 2015 Sep 22. Protein Sci. 2016. PMID: 26293815 Free PMC article. Review.
87 results