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SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.
Lu Q, Liu J, Zhao S, Gomez Castro MF, Laurent-Rolle M, Dong J, Ran X, Damani-Yokota P, Tang H, Karakousi T, Son J, Kaczmarek ME, Zhang Z, Yeung ST, McCune BT, Chen RE, Tang F, Ren X, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov SB, Zhang Z, Aifantis I, Segal LN, Diamond MS, Khanna KM, Stapleford KA, Cresswell P, Liu Y, Ding S, Xie Q, Wang J. Lu Q, et al. Among authors: segal ln. Immunity. 2021 Jun 8;54(6):1304-1319.e9. doi: 10.1016/j.immuni.2021.05.006. Epub 2021 May 9. Immunity. 2021. PMID: 34048708 Free PMC article.
Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome.
Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal SA, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Pérez-Pérez L, Shen G, Jour G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman DH, Weiden M, Heguy A, Evans L, Uyeki TM, Clemente JC, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst CV, Koide S, Stapleford KA, Khanna KM, Ghedin E, Segal LN. Sulaiman I, et al. Among authors: segal ln. Nat Microbiol. 2021 Oct;6(10):1245-1258. doi: 10.1038/s41564-021-00961-5. Epub 2021 Aug 31. Nat Microbiol. 2021. PMID: 34465900 Free PMC article.
ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection.
Ching KL, de Vries M, Gago J, Dancel-Manning K, Sall J, Rice WJ, Barnett C, Khodadadi-Jamayran A, Tsirigos A, Liang FX, Thorpe LE, Shopsin B, Segal LN, Dittmann M, Torres VJ, Cadwell K. Ching KL, et al. Among authors: segal ln. PLoS Biol. 2022 Sep 13;20(9):e3001754. doi: 10.1371/journal.pbio.3001754. eCollection 2022 Sep. PLoS Biol. 2022. PMID: 36099266 Free PMC article.
Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary T-Helper Cell Type 17 Response that Mitigates Susceptibility to Streptococcus pneumoniae.
Wu BG, Sulaiman I, Tsay JJ, Perez L, Franca B, Li Y, Wang J, Gonzalez AN, El-Ashmawy M, Carpenito J, Olsen E, Sauthoff M, Yie K, Liu X, Shen N, Clemente JC, Kapoor B, Zangari T, Mezzano V, Loomis C, Weiden MD, Koralov SB, D'Armiento J, Ahuja SK, Wu XR, Weiser JN, Segal LN. Wu BG, et al. Among authors: segal ln. Am J Respir Crit Care Med. 2021 May 1;203(9):1099-1111. doi: 10.1164/rccm.202005-1596OC. Am J Respir Crit Care Med. 2021. PMID: 33166473 Free PMC article.
Functional lower airways genomic profiling of the microbiome to capture active microbial metabolism.
Sulaiman I, Wu BG, Li Y, Tsay JC, Sauthoff M, Scott AS, Ji K, Koralov SB, Weiden M, Clemente JC, Jones D, Huang YJ, Stringer KA, Zhang L, Geber A, Banakis S, Tipton L, Ghedin E, Segal LN. Sulaiman I, et al. Among authors: segal ln. Eur Respir J. 2021 Jul 29;58(1):2003434. doi: 10.1183/13993003.03434-2020. Print 2021 Jul. Eur Respir J. 2021. PMID: 33446604 Free PMC article.
Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome.
Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal SA, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman DH, Weiden M, Hegu A, Evans L, Uyeki TM, Clemente JC, De Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst CV, Koide S, Stapleford KA, Khanna KM, Ghedin E, Segal LN. Sulaiman I, et al. Among authors: segal ln. medRxiv [Preprint]. 2021 Feb 26:2021.02.23.21252221. doi: 10.1101/2021.02.23.21252221. medRxiv. 2021. PMID: 33655261 Free PMC article. Updated. Preprint.
Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome.
Sulaiman I, Chung M, Angel L, Koralov S, Wu B, Yeung S, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal S, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman D, Heguy A, Uyeki T, Clemente J, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst C, Koide S, Stapleford K, Khanna K, Ghedin E, Weiden M, Segal L. Sulaiman I, et al. Res Sq [Preprint]. 2021 Mar 29:rs.3.rs-266050. doi: 10.21203/rs.3.rs-266050/v1. Res Sq. 2021. PMID: 33791687 Free PMC article. Updated. Preprint.
Lung Microbiota and Its Impact on the Mucosal Immune Phenotype.
Wu BG, Segal LN. Wu BG, et al. Among authors: segal ln. Microbiol Spectr. 2017 Jun;5(3):10.1128/microbiolspec.BAD-0005-2016. doi: 10.1128/microbiolspec.BAD-0005-2016. Microbiol Spectr. 2017. PMID: 28643622 Free PMC article. Review.
Evidence for Environmental-Human Microbiota Transfer at a Manufacturing Facility with Novel Work-related Respiratory Disease.
Wu BG, Kapoor B, Cummings KJ, Stanton ML, Nett RJ, Kreiss K, Abraham JL, Colby TV, Franko AD, Green FHY, Sanyal S, Clemente JC, Gao Z, Coffre M, Meyn P, Heguy A, Li Y, Sulaiman I, Borbet TC, Koralov SB, Tallaksen RJ, Wendland D, Bachelder VD, Boylstein RJ, Park JH, Cox-Ganser JM, Virji MA, Crawford JA, Edwards NT, Veillette M, Duchaine C, Warren K, Lundeen S, Blaser MJ, Segal LN. Wu BG, et al. Among authors: segal ln. Am J Respir Crit Care Med. 2020 Dec 15;202(12):1678-1688. doi: 10.1164/rccm.202001-0197OC. Am J Respir Crit Care Med. 2020. PMID: 32673495 Free PMC article.
89 results